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A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.

Nicholas Liao

Nat Neurosci. 2019 Jun;22(6):1021-1035.

Van Hove H1,2, Martens L3,4, Scheyltjens I1,2, De Vlaminck K1,2, Pombo Antunes AR1,2, De Prijck S4,5, Vandamme N3,4,6, De Schepper S7, Van Isterdael G4,8, Scott CL4,5,9, Aerts J10, Berx G6,11, Boeckxstaens GE7, Vandenbroucke RE4,12,13, Vereecke L13,14,15, Moechars D10, Guilliams M4,5, Van Ginderachter JA1,2, Saeys Y3,16, Movahedi K17,18.

Author information

  1. Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium.
  2. Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium.
  3. Data Mining and Modeling for Biomedicine, VIB Center for Inflammation Research, Ghent, Belgium.
  4. Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  5. Laboratory of Myeloid Cell Ontogeny and Functional Specialization, VIB Center for Inflammation Research, Ghent, Belgium.
  6. Cancer Research Institute Ghent, Ghent, Belgium.
  7. Department of Chronic Diseases, Metabolism and Ageing, Translational Research Center for Gastrointestinal Disorders, Center of Intestinal Neuro-immune Interactions, KU Leuven, Leuven, Belgium.
  8. VIB Flow Core, VIB Center for Inflammation Research, Ghent, Belgium.
  9. Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
  10. Department of Neuroscience, Janssen Research & Development (a division of Janssen Pharmaceutica NV), Beerse, Belgium.
  11. Molecular and Cellular Oncology Laboratory, Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
  12. Barriers in Inflammation lab, VIB Center for Inflammation Research, Ghent, Belgium.
  13. Ghent Gut Inflammation Group, Ghent University, Ghent, Belgium.
  14. Host-Microbiota Interaction lab, VIB Center for Inflammation Research, Ghent, Belgium.
  15. Department of Rheumatology, University Hospital Ghent, Ghent, Belgium.
  16. Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.
  17. Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium. kiavash.movahedi@vub.vib.be.
  18. Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium. kiavash.movahedi@vub.vib.be.

Presented by Hannah Van Hove