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The extracellular DNA lattice of bacterial biofilms is structurally related to Holliday junction recombination intermediates

Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25068-25077.

Devaraj A1, Buzzo JR1, Mashburn-Warren L1, Gloag ES2, Novotny LA1, Stoodley P2, 3, 4, Bakaletz LO1, 5, Goodman SD5, 6.

  1. Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205.
  2. Department of Orthopedics, The Ohio State University, Columbus, OH 43210.
  3. Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210.
  4. National Centre for Advanced Tribology at Southampton, University of Southampton, Southampton SO17 1BJ, United Kingdom.
  5. Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, Ohio 43210.
  6. Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43205; steven.goodman@nationwidechildrens.org.

Presented by Aishwarya Devaraj