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The Mycobacterium tuberculosis Pup-proteasome system regulates nitrate metabolism through an essential protein quality control pathway.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3202-3210.

Becker SH1, Jastrab JB1, Dhabaria A2, Chaton CT3, Rush JS3, Korotkov KV3, Ueberheide B2, Darwin KH4.

  1. Department of Microbiology, New York University School of Medicine, New York, NY 10016.
  2. Proteomics Laboratory, Division of Advanced Research Technologies, New York University School of Medicine, New York, NY 10016.
  3. Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY 40536.
  4. Department of Microbiology, New York University School of Medicine, New York, NY 10016; heran.darwin@med.nyu.edu.

Presented by Samuel Becker