The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells.

Genes Dev. 2019 Apr 11. (Epub ahead of print)

Ng C1, Aichinger M2, Nguyen T#1, Au C#1, Najar T1, Wu L1, Mesa KR1, Liao W3, Quivy JP4, Hubert B3, Almouzni G4, Zuber J2, Littman DR1, 5.

(# Contributed equally)

  1. The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, New York 10016, USA.
  2. Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), 1030 Vienna, Austria.
  3. New York Genome Center, New York, New York 10013, USA.
  4. UMR3664, Centre National de la Recherche Scientifique, Equipe Labellisée Ligue Contre le Cancer, Institut Curie, PSL Research University, F-75005 Paris, France.
  5. Howard Hughes Medical Institute, New York, New York 10016, USA.

Presented by Charles Ng