Open-channel metal particle superlattices

Nature. 2022 Nov;611(7937):695-701. doi: 10.1038/s41586-022-05291-y.

Yuanwei Li, Wenjie Zhou, Ibrahim Tanriover ... Vinayak P Dravid, Koray Aydin, Chad A Mirkin

Biotechnology, Physical Sciences, BiochemistryNicholas LiaoApril 12, 20232022-11 (Nov)

Non-canonical β-adrenergic activation of ERK at endosomes

Nature. 2022 Nov;611(7934):173-179. doi: 10.1038/s41586-022-05343-3.

Yonghoon Kwon, Sohum Mehta, Mary Clark ... Ha Neul Lee, Roger K Sunahara, Jin Zhang

BiochemistryNicholas LiaoMarch 7, 20232022-11 (Nov)

Antibody targeting of E3 ubiquitin ligases for receptor degradation

Nature. 2022 Oct;610(7930):182-189. doi: 10.1038/s41586-022-05235-6.

Hadir Marei, Wen-Ting K Tsai, Yee-Seir Kee ... Jing Li, Nicholas J Agard, Felipe de Sousa E Melo

Biotechnology, Cancer Biology, BiochemistryNicholas LiaoFebruary 14, 20232022-10 (Oct)

Bending forces and nucleotide state jointly regulate F-actin structure

Nature. 2022 Nov;611(7935):380-386. doi: 10.1038/s41586-022-05366-w.

Matthew J Reynolds, Carla Hachicho, Ayala G Carl, Rui Gong, Gregory M Alushin

Biochemistry, Structural BiologyNicholas LiaoJanuary 6, 20232022-11 (Nov)

Screening for generality in asymmetric catalysis

Nature. 2022 Oct;610(7933):680-686. doi: 10.1038/s41586-022-05263-2.

Corin C Wagen, Spencer E McMinn, Eugene E Kwan, Eric N Jacobsen

Biotechnology, BiochemistryNicholas LiaoDecember 1, 20222022-10 (Oct)

Mass photometry enables label-free tracking and mass measurement of single proteins on lipid bilayers

Nat Methods. 2021 Oct;18(10):1247-1252. doi: 10.1038/s41592-021-01261-w.

Eric D B Foley, Manish S Kushwah, Gavin Young, Philipp Kukura

Biochemistry, BiotechnologyNicholas LiaoSeptember 13, 20222021-10 (Oct)

Spectral entropy outperforms MS/MS dot product similarity for small-molecule compound identification

Nat Methods. 2021 Dec;18(12):1524-1531. doi: 10.1038/s41592-021-01331-z.

Yuanyue Li, Tobias Kind, Jacob Folz, Arpana Vaniya, Sajjan Singh Mehta, Oliver Fiehn

Biotechnology, BiochemistryNicholas LiaoJuly 28, 20222021-12 (Dec)

Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration

Cell Stem Cell. 2021 Nov 4;28(11):1982-1999.e8. doi: 10.1016/j.stem.2021.07.011.

Le Qi, Misty S Martin-Sandoval, Salma Merchant ... Zhiyu Zhao, Michalis Agathocleous, Sean J Morrison

Biochemistry, Cell & Developmental Bio, MetabolismNicholas LiaoJuly 14, 20222021-11 (Nov)

Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes

Nat Methods. 2021 May;18(5):507-519. doi: 10.1038/s41592-021-01128-0.

Kristopher W Brannan, Isaac A Chaim, Ryan J Marina ... Assael A Madrigal, Jason G Underwood, Gene W Yeo

Biochemistry, Biotechnology, Genetics & Genome Biology, GenomicsNicholas LiaoJune 23, 20222021-05 (May)

Brain glycogen serves as a critical glucosamine cache required for protein glycosylation

Cell Metab. 2021 Jul 6;33(7):1404-1417.e9. doi: 10.1016/j.cmet.2021.05.003.

Ramon C Sun, Lyndsay E A Young, Ronald C Bruntz ... Thomas D Hurley, Richard R Drake, Matthew S Gentry

Biochemistry, Neuroscience, MetabolismNicholas LiaoMay 17, 20222021-07 (Jul)

CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo

Nat Biotechnol. 2022 Jan 3. doi: 10.1038/s41587-021-01105-0.

Philipp Reautschnig, Nicolai Wahn, Jacqueline Wettengel ... Lars Zender, Jin Billy Li, Thorsten Stafforst

Biotechnology, Biochemistry, Genetics & Genome BiologyNicholas LiaoFebruary 24, 20222022-01 (Jan)

Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape

Cell Metab. 2021 Nov 2;33(11):2247-2259.e6. doi: 10.1016/j.cmet.2021.10.008.

Giulia Salvadori, Federica Zanardi, Fabio Iannelli, Riccardo Lobefaro, Claudio Vernieri, Valter D Longo

Cancer Biology, Metabolism, BiochemistryNicholas LiaoFebruary 22, 20222021-11 (Nov)

Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components

Neuron. 2021 May 19;109(10):1675-1691.e9. doi: 10.1016/j.neuron.2021.03.026.

Evan Lester, Felicia K Ooi, Nadine Bakkar ... George A Carlson, Stanley B Prusiner, Roy Parker

Neuroscience, Biochemistry, MedicineNicholas LiaoFebruary 15, 20222021-05 (May)

Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD + to alleviate mitochondrial disease

Cell Metab. 2021 Oct 5;33(10):1974-1987.e9. doi: 10.1016/j.cmet.2021.06.013.

Shanshan Liu, Song Fu, Guodong Wang ... Mengqiu Dong, Qinghua Liu, Hui Jiang

Cell & Developmental Bio, Biochemistry, MetabolismNicholas LiaoFebruary 8, 20222021-10 (Oct)

Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication

Cell Metab. 2021 Aug 3;33(8):1685-1700.e9. doi: 10.1016/j.cmet.2021.06.005.

Anne Loft, Ana Jimena Alfaro, Søren Fisker Schmidt ... Mauricio Berriel Diaz, Blagoy Blagoev, Stephan Herzig

Metabolism, Biochemistry, MedicineNicholas LiaoFebruary 3, 20222021-08 (Aug)

A lysine-cysteine redox switch with an NOS bridge regulates enzyme function

Nature. 2021 May;593(7859):460-464. doi: 10.1038/s41586-021-03513-3.

Marie Wensien, Fabian Rabe von Pappenheim, Lisa-Marie Funk ... Ricardo A Mata, Viktor Sautner, Kai Tittmann

BiochemistryNicholas LiaoJanuary 6, 20222021-05 (May)

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

Cell. 2021 Jun 24;184(13):3502-3518.e33. doi: 10.1016/j.cell.2021.04.037.

Olivia Sveidahl Johansen, Tao Ma, Jakob Bondo Hansen ... Camilla Scheele, Susanne Mandrup, Zachary Gerhart-Hines

Metabolism, BiochemistryNicholas LiaoDecember 28, 20212021-06 (Jun)

A condensate-hardening drug blocks RSV replication in vivo

Nature. 2021 Jul;595(7868):596-599. doi: 10.1038/s41586-021-03703-z.

Jennifer Risso-Ballester, Marie Galloux, Jingjing Cao ... Jean-François Eléouët, Marie-Anne Rameix-Welti, Ralf Altmeyer

Medicine, Cell & Developmental Bio, BiochemistryNicholas LiaoDecember 9, 20212021-07 (Jul)