2020-05 (May) — Latest research films — JRNLclub, the online journal club

Posts tagged 2020-05 (May)

Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ

Kethoxal-assisted single-stranded DNA sequencing captures global transcription dynamics and enhancer activity in situ

Nat Methods. 2020 May;17(5):515-523. doi: 10.1038/s41592-020-0797-9.

Tong Wu, Ruitu Lyu, Qiancheng You, Chuan He

Genomics, Biotechnology, BiochemistryNicholas LiaoMay 24, 20212020-05 (May)

Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis

Using genetics to prioritize diagnoses for rheumatology outpatients with inflammatory arthritis

Sci Transl Med. 2020 May 27;12(545):eaay1548. doi: 10.1126/scitranslmed.aay1548.

Rachel Knevel, Saskia le Cessie, Chikashi C Terao ... Katherine P Liao, Elizabeth W Karlson, Soumya Raychaudhuri

Genetics & Genome BiologyNicholas LiaoApril 1, 20212020-05 (May)

Genetic tool development in marine protists: emerging model organisms for experimental cell biology

Genetic tool development in marine protists: emerging model organisms for experimental cell biology

Nat Methods. 2020 May;17(5):481-494. doi: 10.1038/s41592-020-0796-x.

Drahomíra Faktorová, R Ellen R Nisbet, José A Fernández Robledo ... Thomas Mock, Alexandra Z Worden, Julius Lukeš

Genetics & Genome Biology, BiotechnologyNicholas LiaoMarch 30, 20212020-05 (May)

Divergent T follicular helper cell requirement for IgA and IgE production to peanut during allergic sensitization

Divergent T follicular helper cell requirement for IgA and IgE production to peanut during allergic sensitization

Sci Immunol. 2020 May 8;5(47):eaay2754. doi: 10.1126/sciimmunol.aay2754.

Biyan Zhang, Elise Liu, Jake A Gertie ... Katharina Lahl, Uthaman Gowthaman, Stephanie C Eisenbarth

Immunology & MicrobiologyNicholas LiaoOctober 15, 20202020-05 (May)

Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage

Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage

Cell. 2020 May 14;181(4):800-817.e22. doi: 10.1016/j.cell.2020.03.052.

Michele M Nava, Yekaterina A Miroshnikova, Leah C Biggs ... Carien M Niessen, Kris Noel Dahl, Sara A Wickström

Genomics, Cell & Developmental BioNicholas LiaoJuly 27, 20202020-05 (May)

Detection of Deleterious On-Target Effects After HDR-Mediated CRISPR Editing

Detection of Deleterious On-Target Effects After HDR-Mediated CRISPR Editing

Cell Rep. 2020 May 26;31(8):107689.

Isabel Weisheit, Joseph A Kroeger, Rainer Malik ... Angelika Dannert, Martin Dichgans, Dominik Paquet

Genetics & Genome Biology, BiotechnologyNicholas LiaoJune 17, 20202020-05 (May)

FBP1 Loss Disrupts Liver Metabolism and Promotes Tumorigenesis Through a Hepatic Stellate Cell Senescence Secretome

FBP1 Loss Disrupts Liver Metabolism and Promotes Tumorigenesis Through a Hepatic Stellate Cell Senescence Secretome

Nat Cell Biol. 2020 May 4.

Fuming Li, Peiwei Huangyang, Michelle Burrows … Brian Keith, Bo Li, M Celeste Simon

Cancer Biology, MetabolismNicholas LiaoJune 1, 20202020-05 (May)

Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming

Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming

Cell Rep. 2020 May 5;31(5):107604.

McDaniel MM, Kottyan LC, Singh H, Pasare C.

Immunology & MicrobiologyNicholas LiaoMay 5, 20202020-05 (May)