Migration-induced cell shattering due to DOCK8 deficiency causes a type 2-biased helper T cell response

Nat Immunol. 2020 Dec;21(12):1528-1539. doi: 10.1038/s41590-020-0795-1.

Caitlin Schneider, Connie Shen, Angelica A Gopal ... Paul W Wiseman, Helen C Su, Judith N Mandl

Immunology & MicrobiologyNicholas LiaoOctober 26, 20212020-12 (Dec)

Receptor-targeted engineered probiotics mitigate lethal Listeria infection

Nat Commun. 2020 Dec 11;11(1):6344. doi: 10.1038/s41467-020-20200-5.

Rishi Drolia, Mary Anne Roshni Amalaradjou, Valerie Ryan ... Bruce M Applegate, Ramesh Vemulapalli, Arun K Bhunia

MicrobiologyNicholas LiaoSeptember 2, 20212020-12 (Dec)

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

Nat Commun. 2020 Dec 11;11(1):6366. doi: 10.1038/s41467-020-20029-y.

Anne Schuster, Eliane Klein, Virginie Neirinckx ... Barbara Klink, Bjarne Winther Kristensen, Simone P Niclou

Genomics, Medicine, NeuroscienceNicholas LiaoAugust 26, 20212020-12 (Dec)

Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts

Nat Commun. 2020 Dec 9;11(1):6303. doi: 10.1038/s41467-020-20132-0.

Nicky Atkinson, Yuwei Mao, Kher Xing Chan, Alistair J McCormick

Plant ScienceNicholas LiaoJuly 15, 20212020-12 (Dec)

A collection of bacterial isolates from the pig intestine reveals functional and taxonomic diversity

Nat Commun. 2020 Dec 15;11(1):6389. doi: 10.1038/s41467-020-19929-w.

David Wylensek, Thomas C A Hitch, Thomas Riedel ... Tobias A M Gulder, Jörg Overmann, Thomas Clavel

Metabolism, MicrobiologyNicholas LiaoJune 15, 20212020-12 (Dec)

A ventrolateral medulla-midline thalamic circuit for hypoglycemic feeding

Nat Commun. 2020 Dec 4;11(1):6218. doi: 10.1038/s41467-020-19980-7.

B Sofia Beas, Xinglong Gu, Yan Leng ... Alexxai V Kravitz, Mark A Hoon, Mario A Penzo

Metabolism, NeuroscienceNicholas LiaoJune 8, 20212020-12 (Dec)

Deep learning suggests that gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure

Nat Commun. 2020 Dec 1;11(1):6141. doi: 10.1038/s41467-020-19921-4.

Jan Zrimec, Christoph S Börlin, Filip Buric ... Jens Nielsen, Mats Töpel, Aleksej Zelezniak

Biochemistry, Genetics & Genome BiologyNicholas LiaoMay 27, 20212020-12 (Dec)

Small-molecule-induced polymerization triggers degradation of BCL6

Nature. 2020 Dec;588(7836):164-168. doi: 10.1038/s41586-020-2925-1.

Mikołaj Słabicki, Hojong Yoon, Jonas Koeppel ... Radosław P Nowak, Eric S Fischer, Benjamin L Ebert

BiochemistryNicholas LiaoMay 20, 20212020-12 (Dec)

Single cell analysis reveals distinct immune landscapes in transplant and primary sarcomas that determine response or resistance to immunotherapy

Nat Commun. 2020 Dec 17;11(1):6410. doi: 10.1038/s41467-020-19917-0.

Amy J Wisdom, Yvonne M Mowery, Cierra S Hong ... Maximilian Diehn, Todd Bradley, David G Kirsch

Cancer Biology, GenomicsNicholas LiaoMay 13, 20212020-12 (Dec)

The iron-dependent repressor YtgR is a tryptophan-dependent attenuator of the trpRBA operon in Chlamydia trachomatis

Nat Commun. 2020 Dec 22;11(1):6430. doi: 10.1038/s41467-020-20181-5.

Nick D Pokorzynski, Nathan D Hatch, Scot P Ouellette, Rey A Carabeo

Cell & Developmental BioNicholas LiaoMay 11, 20212020-12 (Dec)

Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis

Cell. 2020 Dec 10;183(6):1617-1633.e22. doi: 10.1016/j.cell.2020.11.012.

Carol C L Chen, Shriya Deshmukh, Selin Jessa ... Paolo Salomoni, Claudia L Kleinman, Nada Jabado

Medicine, Cancer Biology, Genetics & Genome BiologyNicholas LiaoApril 27, 20212020-12 (Dec)

An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease

Sci Transl Med. 2020 Dec 9;12(573):eabb1206. doi: 10.1126/scitranslmed.abb1206.

Anamitra Ghosh, Michele M Comerota, Debin Wan ... Sung Hee Hwang, Bruce D Hammock, Hui Zheng

Neuroscience, Biochemistry, MedicineNicholas LiaoApril 8, 20212020-12 (Dec)

Serotonin Receptor 2A Activation Promotes Evolutionarily Relevant Basal Progenitor Proliferation in the Developing Neocortex

Neuron. 2020 Dec 23;108(6):1113-1129.e6. doi: 10.1016/j.neuron.2020.09.034.

Lei Xing, Nereo Kalebic, Takashi Namba, Samir Vaid, Pauline Wimberger, Wieland B Huttner

NeuroscienceNicholas LiaoFebruary 23, 20212020-12 (Dec)

Sensory Discrimination of Blood and Floral Nectar by Aedes aegypti Mosquitoes

Neuron. 2020 Dec 23;108(6):1163-1180.e12. doi: 10.1016/j.neuron.2020.09.019.

Veronica Jové, Zhongyan Gong, Felix J H Hol ... Manu Prakash, Carolyn S McBride, Leslie B Vosshall

NeuroscienceNicholas LiaoFebruary 11, 20212020-12 (Dec)

Opposing Influence of Top-down and Bottom-up Input on Excitatory Layer 2/3 Neurons in Mouse Primary Visual Cortex

Neuron. 2020 Dec 23;108(6):1194-1206.e5. doi: 10.1016/j.neuron.2020.09.024.

Rebecca Jordan, Georg B Keller

NeuroscienceNicholas LiaoJanuary 26, 20212020-12 (Dec)

Structure of the shutdown state of myosin-2

Nature. 2020 Dec;588(7838):515-520. doi: 10.1038/s41586-020-2990-5.

Charlotte A Scarff, Glenn Carrington, David Casas-Mao ... Peter J Knight, Neil A Ranson, Michelle Peckham

Structural BiologyNicholas LiaoJanuary 21, 20212020-12 (Dec)

Rescuing Over-activated Microglia Restores Cognitive Performance in Juvenile Animals of the Dp(16) Mouse Model of Down Syndrome

Neuron. 2020 Dec 9;108(5):887-904.e12. doi: 10.1016/j.neuron.2020.09.010.

Bruno Pinto, Giovanni Morelli, Mohit Rastogi ... Andrea Contestabile, Laura E Perlini, Laura Cancedda

Neuroscience, MedicineNicholas LiaoJanuary 19, 20212020-12 (Dec)

Structure of the class D GPCR Ste2 dimer coupled to two G proteins

Nature. 2020 Dec 2. doi: 10.1038/s41586-020-2994-1.

Vaithish Velazhahan, Ning Ma, Gáspár Pándy-Szekeres ... David E Gloriam, Nagarajan Vaidehi, Christopher G Tate

Structural BiologyNicholas LiaoJanuary 7, 20212020-12 (Dec)