Open-channel metal particle superlattices

Nature. 2022 Nov;611(7937):695-701. doi: 10.1038/s41586-022-05291-y.

Yuanwei Li, Wenjie Zhou, Ibrahim Tanriover ... Vinayak P Dravid, Koray Aydin, Chad A Mirkin

Biotechnology, Physical Sciences, BiochemistryNicholas LiaoApril 12, 20232022-11 (Nov)

Antibody targeting of E3 ubiquitin ligases for receptor degradation

Nature. 2022 Oct;610(7930):182-189. doi: 10.1038/s41586-022-05235-6.

Hadir Marei, Wen-Ting K Tsai, Yee-Seir Kee ... Jing Li, Nicholas J Agard, Felipe de Sousa E Melo

Biotechnology, Cancer Biology, BiochemistryNicholas LiaoFebruary 14, 20232022-10 (Oct)

Mitochondrial base editor induces substantial nuclear off-target mutations

Nature. 2022 Jun;606(7915):804-811. doi: 10.1038/s41586-022-04836-5.

Zhixin Lei, Haowei Meng, Lulu Liu ... Min Liu, Aibin He, Chengqi Yi

Biotechnology, Genetics & Genome BiologyNicholas LiaoFebruary 2, 20232022-06 (Jun)

Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL

Nature. 2022 Sep;609(7926):369-374. doi: 10.1038/s41586-022-05140-y.

Jiqin Zhang, Yongxian Hu, Jiaxuan Yang ... Bing Du, Mingyao Liu, He Huang

Biotechnology, Cancer Biology, Immunology & MicrobiologyNicholas LiaoJanuary 10, 20232022-09 (Sep)

Screening for generality in asymmetric catalysis

Nature. 2022 Oct;610(7933):680-686. doi: 10.1038/s41586-022-05263-2.

Corin C Wagen, Spencer E McMinn, Eugene E Kwan, Eric N Jacobsen

Biotechnology, BiochemistryNicholas LiaoDecember 1, 20222022-10 (Oct)

SnapHiC: a computational pipeline to identify chromatin loops from single-cell Hi-C data

Nat Methods. 2021 Sep;18(9):1056-1059. doi: 10.1038/s41592-021-01231-2.

Miao Yu, Armen Abnousi, Yanxiao Zhang ... Yun Li, Bing Ren, Ming Hu

Genetics & Genome Biology, BiotechnologyNicholas LiaoOctober 27, 20222021-09 (Sep)

Experimental reproducibility limits the correlation between mRNA and protein abundances in tumor proteomic profiles

Cell Rep Methods. 2022 Sep 8;2(9):100288. doi: 10.1016/j.crmeth.2022.100288.

Swathi Ramachandra Upadhya, Colm J Ryan

Biotechnology, Genetics & Genome Biology, Cancer BiologyNicholas LiaoOctober 25, 20222022-09 (Sep)

Engineering luminescent biosensors for point-of-care SARS-CoV-2 antibody detection

Nat Biotechnol. 2021 Aug;39(8):928-935. doi: 10.1038/s41587-021-00878-8.

Susanna K Elledge, Xin X Zhou, James R Byrnes ... Kevin K Leung, Bryan Greenhouse, James A Wells

Biotechnology, Medicine, Immunology & MicrobiologyNicholas LiaoSeptember 15, 20222021-08 (Aug)

Mass photometry enables label-free tracking and mass measurement of single proteins on lipid bilayers

Nat Methods. 2021 Oct;18(10):1247-1252. doi: 10.1038/s41592-021-01261-w.

Eric D B Foley, Manish S Kushwah, Gavin Young, Philipp Kukura

Biochemistry, BiotechnologyNicholas LiaoSeptember 13, 20222021-10 (Oct)

Fast optical recording of neuronal activity by three-dimensional custom-access serial holography

Nat Methods. 2022 Jan;19(1):100-110. doi: 10.1038/s41592-021-01329-7.

Walther Akemann, Sébastien Wolf, Vincent Villette ... Jean-François Léger, Stéphane Dieudonné, Laurent Bourdieu

Biotechnology, NeuroscienceNicholas LiaoAugust 25, 20222022-01 (Jan)

Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism

Sci Transl Med. 2021 May 19;13(594):eaaw1564. doi: 10.1126/scitranslmed.aaw1564.

Joanne Ng, Serena Barral, Carmen De La Fuente Barrigon ... Maximilien Bencze, Simon N Waddington, Manju A Kurian

Biotechnology, Medicine, NeuroscienceNicholas LiaoAugust 9, 20222021-05 (May)

Spectral entropy outperforms MS/MS dot product similarity for small-molecule compound identification

Nat Methods. 2021 Dec;18(12):1524-1531. doi: 10.1038/s41592-021-01331-z.

Yuanyue Li, Tobias Kind, Jacob Folz, Arpana Vaniya, Sajjan Singh Mehta, Oliver Fiehn

Biotechnology, BiochemistryNicholas LiaoJuly 28, 20222021-12 (Dec)

Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines

Nat Methods. 2022 Mar;19(3):353-358. doi: 10.1038/s41592-022-01394-6.

Venu G Bandi, Michael P Luciano, Mara Saccomano ... Joseph Ivanic, Oliver T Bruns, Martin J Schnermann

BiotechnologyNicholas LiaoJune 28, 20222022-03 (Mar)

Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes

Nat Methods. 2021 May;18(5):507-519. doi: 10.1038/s41592-021-01128-0.

Kristopher W Brannan, Isaac A Chaim, Ryan J Marina ... Assael A Madrigal, Jason G Underwood, Gene W Yeo

Biochemistry, Biotechnology, Genetics & Genome Biology, GenomicsNicholas LiaoJune 23, 20222021-05 (May)

Detect-seq reveals out-of-protospacer editing and target-strand editing by cytosine base editors

Nat Methods. 2021 Jun;18(6):643-651. doi: 10.1038/s41592-021-01172-w.

Zhixin Lei, Haowei Meng, Zhicong Lv ... Kailin Yin, Yongchang Yan, Chengqi Yi

Genetics & Genome Biology, BiotechnologyNicholas LiaoMay 5, 20222021-06 (Jun)

Curated variation benchmarks for challenging medically relevant autosomal genes

Nat Biotechnol. 2022 Feb 7. doi: 10.1038/s41587-021-01158-1.

Justin Wagner, Nathan D Olson, Lindsay Harris ... Chen-Shan Chin, Justin M Zook, Fritz J Sedlazeck

Biotechnology, Genetics & Genome Biology, MedicineNicholas LiaoApril 28, 20222022-02 (Feb)

Spatial tissue profiling by imaging-free molecular tomography

Nat Biotechnol. 2021 Aug;39(8):968-977. doi: 10.1038/s41587-021-00879-7.

Halima Hannah Schede, Christian G Schneider, Johanna Stergiadou ... Maria Antonietta Tosches, Simone Codeluppi, Gioele La Manno

Biotechnology, Genomics, NeuroscienceNicholas LiaoMarch 24, 20222021-08 (Aug)

CLUSTER guide RNAs enable precise and efficient RNA editing with endogenous ADAR enzymes in vivo

Nat Biotechnol. 2022 Jan 3. doi: 10.1038/s41587-021-01105-0.

Philipp Reautschnig, Nicolai Wahn, Jacqueline Wettengel ... Lars Zender, Jin Billy Li, Thorsten Stafforst

Biotechnology, Biochemistry, Genetics & Genome BiologyNicholas LiaoFebruary 24, 20222022-01 (Jan)