Obese Individuals With and Without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition

Cell Host Microbe. 2019 Aug 14;26(2):252-264.e10. doi: 10.1016/j.chom.2019.07.004.

Louise B Thingholm, Malte C Rühlemann, Manja Koch ... Matthias Laudes, Andre Franke, Curtis Huttenhower

Metabolism, Medicine, Immunology & Microbiology, GenomicsNicholas LiaoJuly 13, 20202019-08 (Aug)

Combination PD-1 and PD-L1 Blockade Promotes Durable Neoantigen-Specific T Cell-Mediated Immunity in Pancreatic Ductal Adenocarcinoma

Cell Rep. 2019 Aug 20;28(8):2140-2155.e6. doi: 10.1016/j.celrep.2019.07.059.

Adam L Burrack, Ellen J Spartz, Jackson F Raynor, Iris Wang, Margaret Olson, Ingunn M Stromnes

Cancer Biology, Immunology & MicrobiologyNicholas LiaoJune 27, 20202019-08 (Aug)

Cholera Toxin Promotes Pathogen Acquisition of Host-Derived Nutrients

Nature. 2019 Aug;572(7768):244-248. doi: 10.1038/s41586-019-1453-3.

Fabian Rivera-Chávez, John J Mekalanos

Immunology & MicrobiologyNicholas LiaoJune 21, 20202019-08 (Aug)

HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding

Mol Cell. 2019 Aug 22;75(4):711-724.e5. doi: 10.1016/j.molcel.2019.05.034.

Joshua J Gruber, Benjamin Geller, Andrew M Lipchik ... James M Ford, Calvin J Kuo, Michael P Snyder

Biochemistry, Metabolism, Genetics & Genome BiologyNicholas LiaoJune 13, 20202019-08 (Aug)

Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss.

Cell Metab. 2019 Aug 6;30(2):261-273.e6.

Lina Aguirre, Georgia Colleluori, Uma Phadnis ... Kevin Yarasheski, Clifford Qualls, Dennis T Villareal

MetabolismNicholas LiaoMay 24, 20202019-08 (Aug)

LncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA

Mol Cell. 2019 Aug 8;75(3):523-537.e10.

Schertzer MD, Braceros KCA, Starmer J, Dowen JM, Magnuson T, Calabrese JM.

Cell & Developmental Bio, Genetics & Genome BiologyNicholas LiaoApril 30, 20202019-08 (Aug)

Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides.

Dev Cell. 2019 Aug 19;50(4):397-410.e3.

Ostrowski PP, Freeman SA, Fairn G, Grinstein S.

Cell & Developmental BioNicholas LiaoApril 29, 20202019-08 (Aug)

The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression.

Cancer Cell. 2019 Aug 12;36(2):139-155.e10

Su W, Han HH, Wang Y…Scher H, Ouerfelli O, Giancotti FG.

Proximity RNA Labeling by APEX-Seq Reveals the Organization of Translation Initiation Complexes and Repressive RNA Granules.

Mol Cell. 2019 Aug 22;75(4):875-887.e5.

Padrón A, Iwasaki S, Ingolia NT.

Biochemistry, Cell & Developmental Bio, GenomicsDavid CantorMarch 31, 20202019-08 (Aug)

TREM2 function impedes tau seeding in neuritic plaques.

Nat Neurosci. 2019 Aug;22(8):1217-1222.

Leyns CEG, Gratuze M, Narasimhan S, Jain N, Koscal LJ, Jiang H, Manis M, Colonna M, Lee VMY, Ulrich JD, Holtzman DM.

NeuroscienceVictoria FangMarch 20, 20202019-08 (Aug)

Multispecific anti-HIV duoCAR-T cells display broad in vitro antiviral activity and potent in vivo elimination of HIV-infected cells in a humanized mouse model.

Sci Transl Med. 2019 Aug 7;11(504).

Anthony-Gonda K#, Bardhi A#, Ray A, Flerin N, Li M… Dimitrov DS, Goldstein H, Dropulić B.

Immunology & Microbiology, Medicine, BiochemistryVictoria FangJanuary 29, 20202019-08 (Aug)

A Reverse Ecology Approach Based on a Biological Definition of Microbial Populations

Cell. 2019 Aug 8;178(4):820-834.e14

Arevalo P, VanInsberghe D, Elsherbini J, Gore J, Polz MF.

Genomics, Medicine, Immunology & Microbiology, Genetics & Genome BiologyVictoria FangJanuary 16, 20202019-08 (Aug)

Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver

Cell. 2019 Aug 22;178(5):1205-1221.e17.

Choudhury SR, Babes L, Rahn JJ, Ahn BY, Goring KR, King JC…Robbins SM, Senger DL.

Immunology & MicrobiologyVictoria FangJanuary 14, 20202019-08 (Aug)

Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet

Cell. 2019 Aug 22;178(5):1115-1131.e15.

Cheng CW, Biton M, Haber AL, Gunduz N, Eng G, Gaynor LT, Tripathi S, Calibasi-Kocal G, Rickelt S, Butty VL, Moreno-Serrano M…Regev A, Yilmaz ÖH.

Metabolism, Cell & Developmental BioVictoria FangJanuary 10, 20202019-08 (Aug)

Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture

Despang A, Schöpflin R, Franke M, Ali S, Jerković I, Paliou C, Chan WL, Timmermann B, Wittler L, Vingron M, Mundlos S, Ibrahim DM.

Nat Genet. 2019 Aug;51(8):1263-1271.

Genomics, Genetics & Genome BiologyVictoria FangNovember 24, 20192019-08 (Aug)

Metastatic-niche labelling reveals parenchymal cells with stem features

Ombrato L, Nolan E, Kurelac I, Mavousian A, Bridgeman VL, Heinze I, Chakravarty P, Horswell S, Gonzalez-Gualda E, Matacchione G, Weston A, Kirkpatrick J, Husain E, Speirs V, Collinson L, Ori A, Lee JH, Malanchi I.

Nature. 2019 Aug;572(7771):603-608.

Cancer Biology, Cell & Developmental BioVictoria FangNovember 11, 20192019-08 (Aug)

Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis.

Henderson MX, Cornblath EJ, Darwich A, Zhang B, Brown H, Gathagan RJ, Sandler RM, Bassett DS, Trojanowski JQ, Lee VMY.

Nat Neurosci. 2019 Aug;22(8):1248-1257.

NeuroscienceVictoria FangNovember 5, 20192019-08 (Aug)

LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription Factors.

Egolf S#, Aubert Y#, Doepner M, Anderson A, Maldonado-Lopez A, Pacella G, Lee J, Ko EK, Zou J, Lan Y, Simpson CL, Ridky T, Capell BC.

#Contributed equally

Cell Rep. 2019 Aug 20;28(8):1981-1992.e7

Cancer Biology, Genetics & Genome BiologyVictoria FangOctober 29, 20192019-08 (Aug)