Metastatic-niche labelling reveals parenchymal cells with stem features

Nature. 2019 Aug;572(7771):603-608.

Ombrato L¹, Nolan E¹, Kurelac I^1.2, Mavousian A³, Bridgeman VL¹, Heinze I⁴, Chakravarty P⁵, Horswell S⁵, Gonzalez-Gualda E¹, Matacchione G¹, Weston A⁶, Kirkpatrick J⁴, Husain E⁷, Speirs V⁸, Collinson L⁶, Ori A⁴, Lee JH^{9, 10}, Malanchi I¹¹.

1. Tumour-Host Interaction Laboratory, The Francis Crick Institute, London, UK.
2. Dipartimento di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna, Italy.
3. Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.
4. Proteomics of Aging, Leibniz Institute on Aging, Fritz Lipmann Institute (FLI), Jena, Germany.
5. Bioinformatics and Biostatistics Unit, The Francis Crick Institute, London, UK.
6. Electron Microscopy Unit, The Francis Crick Institute, London, UK.
7. Department of Pathology, Aberdeen Royal Infirmary, Aberdeen, UK.
8. Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.
9. Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. jhl62@cam.ac.uk.
10. Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. jhl62@cam.ac.uk.
11. Tumour-Host Interaction Laboratory, The Francis Crick Institute, London, UK. Ilaria.Malanchi@crick.ac.uk.

Presented by Luigi Ombrato