A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy.

Xu Y1, Zhou P2, Cheng S3, Lu Q2, Nowak K4, Hopp AK4, Li L2, Shi X2, Zhou Z2, Gao W2, Li D2, He H2, Liu X3, Ding J5, Hottiger MO4, Shao F6.

  1. College of Biological Sciences, China Agricultural University, 100094 Beijing, China; National Institute of Biological Sciences, Beijing, 102206 Beijing, China.
  2. National Institute of Biological Sciences, Beijing, 102206 Beijing, China.
  3. Institute of Analytical Chemistry & Synthetic and Functional Biomolecules Center, College of Chemistry and Molecular Engineering, Peking University, 100871 Beijing, China.
  4. Department of Molecular Mechanisms of Disease, University of Zurich, 8057 Zurich, Switzerland.
  5. National Institute of Biological Sciences, Beijing, 102206 Beijing, China; National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101 Beijing, China.
  6. National Institute of Biological Sciences, Beijing, 102206 Beijing, China; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, 102206 Beijing, China. Electronic address: shaofeng@nibs.ac.cn.

Presented by Yue Xu

Immunology & Microbiology, BiochemistryVictoria Fang2019-07 (Jul)