2021-05 (May) — Latest research films — JRNLclub, the online journal club

Posts tagged 2021-05 (May)

Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism

Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism

Sci Transl Med. 2021 May 19;13(594):eaaw1564. doi: 10.1126/scitranslmed.aaw1564.

Joanne Ng, Serena Barral, Carmen De La Fuente Barrigon ... Maximilien Bencze, Simon N Waddington, Manju A Kurian

Biotechnology, Medicine, NeuroscienceNicholas LiaoAugust 9, 20222021-05 (May)

Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes

Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes

Nat Methods. 2021 May;18(5):507-519. doi: 10.1038/s41592-021-01128-0.

Kristopher W Brannan, Isaac A Chaim, Ryan J Marina ... Assael A Madrigal, Jason G Underwood, Gene W Yeo

Biochemistry, Biotechnology, Genetics & Genome Biology, GenomicsNicholas LiaoJune 23, 20222021-05 (May)

Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components

Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components

Neuron. 2021 May 19;109(10):1675-1691.e9. doi: 10.1016/j.neuron.2021.03.026.

Evan Lester, Felicia K Ooi, Nadine Bakkar ... George A Carlson, Stanley B Prusiner, Roy Parker

Neuroscience, Biochemistry, MedicineNicholas LiaoFebruary 15, 20222021-05 (May)

A lysine-cysteine redox switch with an NOS bridge regulates enzyme function

A lysine-cysteine redox switch with an NOS bridge regulates enzyme function

Nature. 2021 May;593(7859):460-464. doi: 10.1038/s41586-021-03513-3.

Marie Wensien, Fabian Rabe von Pappenheim, Lisa-Marie Funk ... Ricardo A Mata, Viktor Sautner, Kai Tittmann

BiochemistryNicholas LiaoJanuary 6, 20222021-05 (May)

Microglia use TAM receptors to detect and engulf amyloid β plaques

Microglia use TAM receptors to detect and engulf amyloid β plaques

Nat Immunol. 2021 May;22(5):586-594. doi: 10.1038/s41590-021-00913-5.

Youtong Huang, Kaisa E Happonen, Patrick G Burrola ... Ling Huang, Axel Nimmerjahn, Greg Lemke

NeuroscienceNicholas LiaoDecember 23, 20212021-05 (May)

Cell-programmed nutrient partitioning in the tumour microenvironment

Cell-programmed nutrient partitioning in the tumour microenvironment

Nature. 2021 May;593(7858):282-288. doi: 10.1038/s41586-021-03442-1.

Bradley I Reinfeld, Matthew Z Madden, Melissa M Wolf ... H Charles Manning, Jeffrey C Rathmell, W Kimryn Rathmell

Cancer Biology, MetabolismNicholas LiaoSeptember 23, 20212021-05 (May)

A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease

A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease

Nature. 2021 May;593(7858):275-281. doi: 10.1038/s41586-021-03484-5.

Shikha Nayar, Joshua K Morrison, Mamta Giri ... Miriam Merad, Jaime Chu, Judy H Cho

Medicine, Immunology & MicrobiologyNicholas LiaoSeptember 16, 20212021-05 (May)