Interleukin-2 signals converge in a lymphoid-dendritic cell pathway that promotes anticancer immunity

Sci Transl Med. 2020 Sep 16;12(561):eaba5464. doi: 10.1126/scitranslmed.aba5464.

Miro E Raeber, Rodney A Rosalia, Dominic Schmid, Ufuk Karakus, Onur Boyman

Cancer Biology, Immunology & MicrobiologyNicholas LiaoApril 20, 20212020-09 (Sep)

Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

Cell. 2020 Sep 17;182(6):1419-1440.e23. doi: 10.1016/j.cell.2020.08.001.

Jonas Schulte-Schrepping, Nico Reusch, Daniela Paclik ... Antoine-Emmanuel Saliba, Leif Erik Sander, Deutsche COVID-19 OMICS Initiative (DeCOI)

COVID-19, Medicine, Immunology & MicrobiologyNicholas LiaoApril 6, 20212020-09 (Sep)

B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction

Sci Transl Med. 2020 Sep 16;12(561):eaba5942. doi: 10.1126/scitranslmed.aba5942.

Sujeetha A Rajakumar, Eniko Papp, Kathy K Lee ... Johann K Hitzler, Cynthia J Guidos, Jayne S Danska

Cancer Biology, MedicineNicholas LiaoMarch 23, 20212020-09 (Sep)

Identification of the human DPR core promoter element using machine learning

Nature. 2020 Sep;585(7825):459-463. doi: 10.1038/s41586-020-2689-7.

Long Vo Ngoc, Cassidy Yunjing Huang, California Jack Cassidy, Claudia Medrano, James T Kadonaga

Biochemistry, BiotechnologyNicholas LiaoMarch 11, 20212020-09 (Sep)

Actin chromobody imaging reveals sub-organellar actin dynamics

Nat Methods. 2020 Sep;17(9):917-921. doi: 10.1038/s41592-020-0926-5.

Cara R Schiavon, Tong Zhang, Bing Zhao ... Gerald S Shadel, Robert Grosse, Uri Manor

Cell & Developmental BioNicholas LiaoJanuary 28, 20212020-09 (Sep)

Posterior amygdala regulates sexual and aggressive behaviors in male mice

Nat Neurosci. 2020 Sep;23(9):1111-1124. doi: 10.1038/s41593-020-0675-x.

Takashi Yamaguchi, Dongyu Wei, Soomin C Song, Byungkook Lim, Nicolas X Tritsch, Dayu Lin

NeuroscienceNicholas LiaoJanuary 14, 20212020-09 (Sep)

The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development

Nat Neurosci. 2020 Sep;23(9):1067-1078. doi: 10.1038/s41593-020-0672-0.

Qifei Cong, Breeanne M Soteros, Mackenna Wollet, Jun Hee Kim, Gek-Ming Sia

NeuroscienceNicholas LiaoJanuary 11, 20212020-09 (Sep)

ATR Restrains DNA Synthesis and Mitotic Catastrophe in Response to CDC7 Inhibition

Cell Rep. 2020 Sep 1;32(9):108096. doi: 10.1016/j.celrep.2020.108096.

Michael D Rainey, Declan Bennett, Rachel O'Dea ... Muriel Voisin, Cathal Seoighe, Corrado Santocanale

Biochemistry, Cell & Developmental BioNicholas LiaoDecember 3, 20202020-09 (Sep)

Brain immune cells undergo cGAS-STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I interferon production

J Clin Invest. 2020 Sep 29;136824. doi: 10.1172/JCI136824.

Line S Reinert, Ahmad S Rashidi, Diana N Tran ... Henrik Zetterberg, Georges Mgm Verjans, Soren R Paluden

Immunology & MicrobiologyNicholas LiaoNovember 20, 20202020-09 (Sep)

Phase Separation of a PKA Regulatory Subunit Controls cAMP Compartmentation and Oncogenic Signaling

Cell. 2020 Sep 17;182(6):1531-1544.e15. doi: 10.1016/j.cell.2020.07.043.

Jason Z Zhang, Tsan-Wen Lu, Lucas M Stolerman ... Susan S Taylor, Sohum Mehta, Jin Zhang

Cancer Biology, BiochemistryNicholas LiaoNovember 12, 20202020-09 (Sep)

Neural Stem Cell Grafts Form Extensive Synaptic Networks that Integrate with Host Circuits after Spinal Cord Injury

Cell Stem Cell. 2020 Sep 3;27(3):430-440.e5. doi: 10.1016/j.stem.2020.07.007.

Steven Ceto, Kohei J Sekiguchi, Yoshio Takashima, Axel Nimmerjahn, Mark H Tuszynski

NeuroscienceNicholas LiaoOctober 21, 20202020-09 (Sep)

Mitochondrial ubiquinol oxidation is necessary for tumour growth

Nature. 2020 Sep;585(7824):288-292. doi: 10.1038/s41586-020-2475-6.

Inmaculada Martínez-Reyes, Luzivette Robles Cardona, Hyewon Kong ... Raul Piseaux, G R Scott Budinger, Navdeep S Chandel

Cancer BiologyNicholas LiaoOctober 19, 20202020-09 (Sep)

The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation

Cell Metab. 2020 Sep 1;32(3):468-478.e7. doi: 10.1016/j.cmet.2020.07.016.

Alexander Hooftman, Stefano Angiari, Svenja Hester ... Alan D Irvine, Roman Fischer, Luke A J O'Neill

Immunology & MicrobiologyNicholas LiaoSeptember 28, 20202020-09 (Sep)

Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing

Cell Stem Cell. 2020 Sep 3;27(3):396-412.e6. doi: 10.1016/j.stem.2020.07.008.

Sepideh Abbasi, Sarthak Sinha, Elodie Labit ... Fabio M V Rossi, T Michael Underhill, Jeff Biernaskie

Cell & Developmental BioNicholas LiaoSeptember 24, 20202020-09 (Sep)

Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice

Nat Neurosci. 2020 Sep;23(9):1090-1101. doi: 10.1038/s41593-020-0663-1.

Julie Ouellette, Xavier Toussay, Cesar H Comin ... Dylan Burger, Duncan J Stewart, Baptiste Lacoste

NeuroscienceNicholas LiaoSeptember 21, 20202020-09 (Sep)

Targeting leukocidin-mediated immune evasion protects mice from Staphylococcus aureus bacteremia

J Exp Med. 2020 Sep 7;217(9):e20190541. doi: 10.1084/jem.20190541.

Kayan Tam, Keenan A Lacey, Joseph C Devlin ... Sergei B Koralov, P'ng Loke, Victor J Torres

Immunology & MicrobiologyNicholas LiaoAugust 1, 20202020-09 (Sep)