Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming

Cell Rep. 2020 May 5;31(5):107604.

Margaret M. McDaniel^{1, 2, 3}, Leah C. Kottyan^{4, 5}, Harinder Singh⁶, Chandrashekhar Pasare^{2, 3, 5, 7}

1. Immunology Graduate Program, University of Texas Southwestern Medical Center at Dallas, TX, USA
2. Division of Immunobiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
3. Center for Inflammation and Tolerance, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
4. Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
5. Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, OH, USA
6. Center for Systems Immunology, Departments of Immunology and Computational and Systems Biology, The University of Pittsburgh, Pittsburgh, PA, USA

Presented by Margaret M. McDaniel