Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET.
Lu M1, Ma X1, Castillo-Menendez LR2,3, Gorman J4, Alsahafi N5,6, Ermel U1, Terry DS7, Chambers M4, Peng D4, Zhang B4, Zhou T4, Reichard N1, Wang K1, Grover JR1, Carman BP1, Gardner MR8, Nikić-Spiegel I9, Sugawara A10, Arthos J11, Lemke EA12,13,14, Smith AB 3rd10, Farzan M8, Abrams C15, Munro JB16, McDermott AB4, Finzi A5,6, Kwong PD4, Blanchard SC17, Sodroski JG18,19, Mothes W20.
- Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA.
- Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA.
- Department of Microbiology, Harvard Medical School, Boston, MA, USA.
- Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
- Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada.
- Centre de Recherche du CHUM (CRCHUM), Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montreal, Quebec, Canada.
- Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
- Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, USA.
- Werner Reichardt Centre for Integrative Neuroscience, University of Tuebingen, Tuebingen, Germany.
- Department of Chemistry, University of Pennsylvania, Philadelphia, PA, USA.
- Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
- Departments of Biology and Chemistry, Pharmacy and Geosciences, Johannes Gutenberg University Mainz, Mainz, Germany.
- Institute of Molecular Biology (IMB), Johannes Gutenberg University Mainz, Mainz, Germany.
- Structural and Computational Biology Unit and Cell Biology and Biophysics Unit, EMBL, Heidelberg, Germany.
- Department of Chemical and Biological Engineering, Drexel University, Philadelphia, PA, USA.
- Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA, USA.
- Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA. scb2005@med.cornell.edu.
- Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA. Joseph_Sodroski@dfci.harvard.edu.
- Department of Microbiology, Harvard Medical School, Boston, MA, USA. Joseph_Sodroski@dfci.harvard.edu.
- Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA. walther.mothes@yale.edu.
Presented by Maolin Lu