TREM2 function impedes tau seeding in neuritic plaques.
Leyns CEG1,2,3#, Gratuze M1,2,3#, Narasimhan S4, Jain N1,2,3, Koscal LJ1,2,3, Jiang H1,2,3, Manis M1,2,3, Colonna M2,3,5, Lee VMY4, Ulrich JD6,7,8, Holtzman DM9,10,11.
- Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
- Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA.
- Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA.
- Department of Pathology and Laboratory Medicine, Institute on Aging and Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
- Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
- Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA. ulrichjd@wustl.edu.
- Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. ulrichjd@wustl.edu.
- Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA. ulrichjd@wustl.edu.
- Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA. holtzman@wustl.edu.
- Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, USA. holtzman@wustl.edu.
- Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO, USA. holtzman@wustl.edu.
#Contributed equally
Presented by Cheryl Leyns