Uncoupling the senescence-associated secretory phenotype from cell cycle exit via IL-1 inactivation unveils its pro-tumorigenic role.

Mol Cell Biol. 2019 Apr 15. pii: MCB.00586-18

Lau L¹, Porciuncula A¹, Yu A¹, Iwakura Y², David G^{3, 1}.

1. Department of Biochemistry and Molecular Pharmacology, Deparment of Urology, NYU Cancer Institute, New York University School of Medicine, New York, NY, USA.
2. Research Institute for Biomedical Sciences, Tokyo University of Science, Yamazaki, Noda, Japan.
3. Department of Biochemistry and Molecular Pharmacology, Deparment of Urology, NYU Cancer Institute, New York University School of Medicine, New York, NY, USA.

Presented by Lena Lau