Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor

Basore K1, Kim AS2, Nelson CA1, Zhang R3, Smith BK1, Uranga C4, Vang L4, Cheng M5, Gross ML5, Smith J4, Diamond MS6, Fremont DH7.

  1. Department of Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA.
  2. Department of Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA.
  3. Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA.
  4. PaxVax, San Diego, CA 92121, USA.
  5. Department of Chemistry, Washington University, Saint Louis, MO 63110, USA.
  6. Department of Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address: diamond@wusm.wustl.edu.
  7. Department of Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address: fremont@wustl.edu.

Presented by Katherine Basore