Microglia monitor and protect neuronal function through specialized somatic purinergic junctions.

Cserép C#, 1, Pósfai B#, 1, 2, Lénárt N1, Fekete R1, 2, László ZI2, 3, Lele Z3, Orsolits B1, Molnár G4, Heindl S5, Schwarcz AD1, Ujvári K1, Környei Z1, Tóth K1, 2, Szabadits E1, Sperlágh B6, Baranyi M6, Csiba L7, Hortobágyi T8, 9, 10, Maglóczky Z11, Martinecz B1, Szabó G12, Erdélyi F12, Szipőcs R13, Tamkun MM14, Gesierich B5, Duering M5, 15, Katona I3, Liesz A5, 15, Tamás G4, Dénes Á16.

  1. Momentum Laboratory of Neuroimmunology, Institute of Experimental Medicine, Budapest, Hungary.
  2. Szentágothai János Doctoral School of Neuroscience, Semmelweis University, Budapest, Hungary.
  3. Momentum Laboratory of Molecular Neurobiology, Institute of Experimental Medicine, Budapest, Hungary.
  4. MTA-SZTE Research Group for Cortical Microcircuits of the Hungarian Academy of Sciences, Department of Physiology, Anatomy and Neuroscience, University of Szeged, Szeged, Hungary.
  5. Institute for Stroke and Dementia Research, Ludwig-Maximilians-University, Munich, Germany.
  6. Laboratory of Molecular Pharmacology, Institute of Experimental Medicine, Budapest, Hungary.
  7. MTA-DE Cerebrovascular and Neurodegenerative Research Group, Department of Neurology, University of Debrecen, Debrecen, Hungary.
  8. Institute of Pathology, Faculty of Medicine, University of Szeged, Szeged, Hungary.
  9. Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  10. Centre for Age-Related Medicine, SESAM, Stavanger University Hospital, Stavanger, Norway.
  11. Human Brain Research Laboratory, Institute of Experimental Medicine, Budapest, Hungary.
  12. Medical Gene Technology Unit, Institute of Experimental Medicine, Budapest, Hungary.
  13. Institute for Solid State Physics and Optics of Wigner RCP, Budapest, Hungary.
  14. Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.
  15. Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  16. Momentum Laboratory of Neuroimmunology, Institute of Experimental Medicine, Budapest, Hungary. denes.adam@koki.mta.hu.

#Contributed equally

Presented by Csaba Cserép and Balázs Pósfai

Neuroscience, Cell & Developmental BioVictoria Fang2020-01 (Jan)