Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19

Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z.

Matthew C Woodruff, Richard P Ramonell, Doan C Nguyen ... William T Hu, F Eun-Hyung Lee, Ignacio Sanz

COVID-19, Immunology & Microbiology, MedicineNicholas LiaoDecember 4, 20202020-12 (Dec)

Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction

Cell. 2020 Oct 29;183(3):818-834.e13. doi: 10.1016/j.cell.2020.09.015.

Daniel K Wells, Marit M van Buuren, Kristen K Dang ... Ton N Schumacher, Pia Kvistborg, Nadine A Defranoux

Cancer Biology, MedicineNicholas LiaoNovember 30, 20202020-10 (Oct)

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

Cell. 2020 Oct 29;183(3):636-649.e18. doi: 10.1016/j.cell.2020.09.020.

Chien-Hsiung Yu, Sophia Davidson, Cassandra R Harapas ... Kate McArthur, Peter J Crouch, Seth L Masters

Neuroscience, Immunology & Microbiology, MedicineNicholas LiaoNovember 19, 20202020-10 (Oct)

Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly

Cell. 2020 Oct 15;183(2):315-323.e9. doi: 10.1016/j.cell.2020.08.051.

Evangelos J Giamarellos-Bourboulis, Maria Tsilika, Simone Moorlag ... George Renieris, Antonios Papadopoulos, Mihai G Netea

Immunology & Microbiology, MedicineNicholas LiaoNovember 17, 20202020-10 (Oct)

SARS-CoV-2 seroprevalence among parturient women in Philadelphia

Sci Immunol. 2020 Jul 29;5(49):eabd5709. doi: 10.1126/sciimmunol.abd5709.

Dustin D Flannery, Sigrid Gouma, Miren B Dhudasia ... E John Wherry, Karen M Puopolo, Scott E Hensley

Immunology & Microbiology, Medicine, COVID-19Nicholas LiaoOctober 13, 20202020-07 (Jul)

A case report of clonal EBV-like memory CD4 + T cell activation in fatal checkpoint inhibitor-induced encephalitis

Nat Med. 2019 Aug;25(8):1243-1250. doi: 10.1038/s41591-019-0523-2.

Douglas B Johnson, Wyatt J McDonnell, Paula I Gonzalez-Ericsson ... Melinda E Sanders, Jeffrey A Sosman, Justin M Balko

Medicine, Immunology & MicrobiologyNicholas LiaoOctober 9, 20202019-08

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

Sci Immunol. 2020 Jun 26;5(48):eabd2071. doi: 10.1126/sciimmunol.abd2071.

Daniela Weiskopf, Katharina S Schmitz, Matthijs P Raadsen ... Rik L de Swart, Alessandro Sette, Rory D de Vries

Immunology & Microbiology, Medicine, COVID-19Nicholas LiaoOctober 6, 20202020-06

Adipose tissue-derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases

Sci Transl Med. 2019 Sep 18;11(510):eaav5055. doi: 10.1126/scitranslmed.aav5055.

Ioannis Akoumianakis, Fabio Sanna, Marios Margaritis ... Dimitris Tousoulis, Keith M Channon, Charalambos Antoniades

Metabolism, MedicineNicholas LiaoSeptember 4, 20202019-09 (Sep)

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

Nat Commun. 2020 Jun 19;11(1):3150. doi: 10.1038/s41467-020-16819-z.

Joanne M Hildebrand, Maria Kauppi, Ian J Majewski ... James M Murphy, Warren S Alexander, John Silke

Cell & Developmental Bio, Biochemistry, MedicineNicholas LiaoAugust 20, 20202020-06 (Jun)

Paroxysmal slow cortical activity in Alzheimer's disease and epilepsy is associated with blood-brain barrier dysfunction

Sci Transl Med. 2019 Dec 4;11(521):eaaw8954. doi: 10.1126/scitranslmed.aaw8954.

Dan Z Milikovsky, Jonathan Ofer, Vladimir V Senatorov Jr ... Felix Benninger, Daniela Kaufer, Alon Friedman

Neuroscience, MedicineNicholas LiaoAugust 17, 20202019-12 (Dec)

Obese Individuals With and Without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition

Cell Host Microbe. 2019 Aug 14;26(2):252-264.e10. doi: 10.1016/j.chom.2019.07.004.

Louise B Thingholm, Malte C Rühlemann, Manja Koch ... Matthias Laudes, Andre Franke, Curtis Huttenhower

Metabolism, Medicine, Immunology & Microbiology, GenomicsNicholas LiaoJuly 13, 20202019-08 (Aug)

Mouse Models of Neutropenia Reveal Progenitor-Stage-Specific Defects

Nature. 2020 Jun;582(7810):109-114. doi: 10.1038/s41586-020-2227-7.

David E Muench, Andre Olsson, Kyle Ferchen ... Sing Sing Way, Nathan Salomonis, H Leighton Grimes

Cell & Developmental Bio, Genomics, MedicineNicholas LiaoJuly 9, 20202020-06 (Jun)

Elite Control of HIV Is Associated With Distinct Functional and Transcriptional Signatures in Lymphoid Tissue CD8 + T Cells

Sci Transl Med. 2019 Dec 18;11(523):eaax4077. doi: 10.1126/scitranslmed.aax4077.

Son Nguyen, Claire Deleage, Samuel Darko ... Steven G Deeks, Marcus Buggert, Michael R Betts

Immunology & Microbiology, MedicineNicholas LiaoJuly 1, 20202019-12 (Dec)

Glutamine Links Obesity to Inflammation in Human White Adipose Tissue

Cell Metab. 2020 Feb 4;31(2):375-390.e11. doi: 10.1016/j.cmet.2019.11.019.

Paul Petrus, Simon Lecoutre, Lucile Dollet ... Myriam Aouadi, Anna Krook, Mikael Rydén

Metabolism, Biochemistry, MedicineNicholas LiaoJune 18, 20202020-02 (Feb)

A Sensory Appendage Protein Protects Malaria Vectors From Pyrethroids

Nature. 2020 Jan;577(7790):376-380. doi: 10.1038/s41586-019-1864-1.

Victoria A Ingham, Amalia Anthousi, Vassilis Douris ... Marion Morris, John Vontas, Hilary Ranson

Medicine, Cell & Developmental BioNicholas LiaoJune 16, 20202020-01 (Jan)

Prunin Suppresses Viral IRES Activity and Is a Potential Candidate for Treating Enterovirus A71 Infection

Sci Transl Med. 2019 Oct 30;11(516):eaar5759.

Saravanan Gunaseelan, Kai Zhi Wong, Nyo Min … Yee Joo Tan, Regina Ching Hua Lee, Justin Jang Hann Chu

Immunology & Microbiology, MedicineNicholas LiaoMay 30, 20202019-10 (Oct)

Sodium Chloride Is an Ionic Checkpoint for Human TH2 Cells and Shapes the Atopic Skin Microenvironment

Sci Transl Med. 2019 Feb 20;11(480):eaau0683.

Julia Matthias, Julia Maul, Rebecca Noster … Tilo Biedermann, Dirk Baumjohann, Christina E Zielinski

Immunology & Microbiology, MedicineNicholas LiaoMay 29, 20202019-02 (Feb)

Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis.

Sci Transl Med. 2019 Nov 13;11(518).

Mishra R, Kohli S, Malhotra N, …, Rajmani RS, Seshasayee ASN, Singh A.

Medicine, Immunology & MicrobiologyNicholas LiaoMay 23, 20202019-11 (Nov)