Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development.

Cell Metab. 2019 Feb 5;29(2):348-361.e6. doi: 10.1016/j.cmet.2018.09.011.

Claudiane Guay, Janine K Kruit, Sophie Rome ... Pedro Romero, Francesco Dotta, Romano Regazzi

Metabolism, Immunology & MicrobiologyNicholas LiaoJuly 3, 20202019-02 (Feb)

Elite Control of HIV Is Associated With Distinct Functional and Transcriptional Signatures in Lymphoid Tissue CD8 + T Cells

Sci Transl Med. 2019 Dec 18;11(523):eaax4077. doi: 10.1126/scitranslmed.aax4077.

Son Nguyen, Claire Deleage, Samuel Darko ... Steven G Deeks, Marcus Buggert, Michael R Betts

Immunology & Microbiology, MedicineNicholas LiaoJuly 1, 20202019-12 (Dec)

Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis

Cell Metab. 2020 Jan 7;31(1):115-130.e6. doi: 10.1016/j.cmet.2019.10.005.

Nupur K Das, Andrew J Schwartz, Gabrielle Barthel ... Duxin Sun, Vincent B Young, Yatrik M Shah

Metabolism, Immunology & MicrobiologyNicholas LiaoJune 29, 20202020-01 (Jan)

Combination PD-1 and PD-L1 Blockade Promotes Durable Neoantigen-Specific T Cell-Mediated Immunity in Pancreatic Ductal Adenocarcinoma

Cell Rep. 2019 Aug 20;28(8):2140-2155.e6. doi: 10.1016/j.celrep.2019.07.059.

Adam L Burrack, Ellen J Spartz, Jackson F Raynor, Iris Wang, Margaret Olson, Ingunn M Stromnes

Cancer Biology, Immunology & MicrobiologyNicholas LiaoJune 27, 20202019-08 (Aug)

Intermittent Rolling Is a Defect of the Extravasation Cascade Caused by Myosin1e-deficiency in Neutrophils

Proc Natl Acad Sci U S A. 2019 Dec 6;116(52):26752-26758. doi: 10.1073/pnas.1902502116.

Eduardo Vadillo, Sandra Chánez-Paredes, Hilda Vargas-Robles ... Daniel Alberto Girón-Pérez, Leopoldo Santos-Argumedo, Michael Schnoor

Cell & Developmental Bio, Immunology & MicrobiologyNicholas LiaoJune 25, 20202019-12 (Dec)

Targeting Peripheral CB 1 Receptors Reduces Ethanol Intake via a Gut-Brain Axis

Cell Metab. 2019 Jun 4;29(6):1320-1333.e8. doi: 10.1016/j.cmet.2019.04.012.

Grzegorz Godlewski, Resat Cinar, Nathan J Coffey ... Roy G Smith, Hiroshi Iwakura, George Kunos

Metabolism, BiochemistryNicholas LiaoJune 24, 20202019-06 (Jun)

Cholera Toxin Promotes Pathogen Acquisition of Host-Derived Nutrients

Nature. 2019 Aug;572(7768):244-248. doi: 10.1038/s41586-019-1453-3.

Fabian Rivera-Chávez, John J Mekalanos

Immunology & MicrobiologyNicholas LiaoJune 21, 20202019-08 (Aug)

Broad Heterochromatic Domains Open in Gonocyte Development Prior to De Novo DNA Methylation

Dev Cell. 2019 Oct 7;51(1):21-34.e5. doi: 10.1016/j.devcel.2019.07.023.

Soichiro Yamanaka, Hidenori Nishihara, Hidehiro Toh ... Piero Carninci, Hiroyuki Sasaki, Haruhiko Siomi

Genetics & Genome BiologyNicholas LiaoJune 19, 20202019-10 (Oct)

Glutamine Links Obesity to Inflammation in Human White Adipose Tissue

Cell Metab. 2020 Feb 4;31(2):375-390.e11. doi: 10.1016/j.cmet.2019.11.019.

Paul Petrus, Simon Lecoutre, Lucile Dollet ... Myriam Aouadi, Anna Krook, Mikael Rydén

Metabolism, Biochemistry, MedicineNicholas LiaoJune 18, 20202020-02 (Feb)

Detection of Deleterious On-Target Effects After HDR-Mediated CRISPR Editing

Cell Rep. 2020 May 26;31(8):107689.

Isabel Weisheit, Joseph A Kroeger, Rainer Malik ... Angelika Dannert, Martin Dichgans, Dominik Paquet

Genetics & Genome Biology, BiotechnologyNicholas LiaoJune 17, 20202020-05 (May)

A Sensory Appendage Protein Protects Malaria Vectors From Pyrethroids

Nature. 2020 Jan;577(7790):376-380. doi: 10.1038/s41586-019-1864-1.

Victoria A Ingham, Amalia Anthousi, Vassilis Douris ... Marion Morris, John Vontas, Hilary Ranson

Medicine, Cell & Developmental BioNicholas LiaoJune 16, 20202020-01 (Jan)

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4 + T Cell Pathogenicity and Suppresses Autoimmunity

Cell Metab. 2020 Feb 4;31(2):391-405.e8.

Stefano Angiari, Marah C Runtsch, Caroline E Sutton ... Erika L Pearce, Kingston H G Mills, Luke A J O'Neill

Immunology & Microbiology, MetabolismNicholas LiaoJune 15, 20202020-02 (Feb)

HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding

Mol Cell. 2019 Aug 22;75(4):711-724.e5. doi: 10.1016/j.molcel.2019.05.034.

Joshua J Gruber, Benjamin Geller, Andrew M Lipchik ... James M Ford, Calvin J Kuo, Michael P Snyder

Biochemistry, Metabolism, Genetics & Genome BiologyNicholas LiaoJune 13, 20202019-08 (Aug)

Programmable Inhibition and Detection of RNA Viruses Using Cas13

Mol Cell. 2019 Dec 5;76(5):826-837.e11.

Cameron Myhrvold, Catherine A Freije, Chloe K Boehm ... Nathan L Yozwiak, Feng Zhang, Pardis C Sabeti

Cell & Developmental Bio, Immunology & MicrobiologyNicholas LiaoJune 12, 20202019-12 (Dec)

A Farnesyltransferase Inhibitor Activates Lysosomes and Reduces Tau Pathology in Mice With Tauopathy

Sci Transl Med. 2019 Mar 27;11(485):eaat3005.

Israel Hernandez, Gabriel Luna, Jennifer N Rauch ... Steven K Fisher, Ana M Cuervo, Kenneth S Kosik

NeuroscienceNicholas LiaoJune 11, 20202019-03 (Mar)

Cas9 Cleavage of Viral Genomes Primes the Acquisition of New Immunological Memories

Cell Host Microbe. 2019 Oct 9;26(4):515-526.e6.

Philip M Nussenzweig, Jon McGinn, Luciano A Marraffini

Immunology & MicrobiologyNicholas LiaoJune 8, 20202019-10 (Oct)

The Long Noncoding RNA Pnky Is a Trans-acting Regulator of Cortical Development In Vivo

Dev Cell. 2019 May 20;49(4):632-642.e7.

Rebecca E Andersen, Sung Jun Hong, Justin J Lim … Siyuan John Liu, Benjamin J Blencowe, Daniel A Lim

Cell & Developmental Bio, NeuroscienceNicholas LiaoJune 6, 20202019-05 (May)

Structures of Neisseria Meningitidis Cas9 Complexes in Catalytically Poised and Anti-CRISPR-Inhibited States

Mol Cell. 2019 Dec 19;76(6):938-952.e5.

Wei Sun, Jing Yang, Zhi Cheng … Jizhong Lou, Erik J Sontheimer, Yanli Wang

Structural BiologyNicholas LiaoJune 5, 20202019-12 (Dec)