Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation

Cell Host Microbe. 2020 Apr 8;27(4):614-628.e6.

Darin L Wiesner, Richard M Merkhofer, Carole Ober … Hongmei Mou, Jatin M Vyas, Bruce S Klein

Immunology & MicrobiologyNicholas LiaoJune 4, 20202020-04 (Apr)

Live-Cell Single RNA Imaging Reveals Bursts of Translational Frameshifting

Mol Cell. 2019 Jul 11;75(1):172-183.e9.

Kenneth Lyon, Luis U Aguilera, Tatsuya Morisaki, Brian Munsky, Timothy J Stasevich

Cell & Developmental BioNicholas LiaoJune 2, 20202019-07 (Jul)

A Bioinformatic Analysis of Integrative Mobile Genetic Elements Highlights Their Role in Bacterial Adaptation

Cell Host Microbe. 2020 Jan 8;27(1):140-153.e9.

Matthew G Durrant, Michelle M Li, Benjamin A Siranosian, Stephen B Montgomery, Ami S Bhatt

Immunology & Microbiology, GenomicsNicholas LiaoJune 1, 20202020-01 (Jan)

FBP1 Loss Disrupts Liver Metabolism and Promotes Tumorigenesis Through a Hepatic Stellate Cell Senescence Secretome

Nat Cell Biol. 2020 May 4.

Fuming Li, Peiwei Huangyang, Michelle Burrows … Brian Keith, Bo Li, M Celeste Simon

Cancer Biology, MetabolismNicholas LiaoJune 1, 20202020-05 (May)

Human Cytomegalovirus miRNAs Regulate TGF-β to Mediate Myelosuppression While Maintaining Viral Latency in CD34 + Hematopoietic Progenitor Cells

Cell Host Microbe 2020 Jan 8;27(1):104-114.e4.

Meaghan H Hancock #, Lindsey B Crawford #, Andrew H Pham … Andrew D Yurochko, Patrizia Caposio, Jay A Nelson

#Contributed Equally

Cell & Developmental Bio, Immunology & MicrobiologyNicholas LiaoMay 30, 20202020-01 (Jan)

Prunin Suppresses Viral IRES Activity and Is a Potential Candidate for Treating Enterovirus A71 Infection

Sci Transl Med. 2019 Oct 30;11(516):eaar5759.

Saravanan Gunaseelan, Kai Zhi Wong, Nyo Min … Yee Joo Tan, Regina Ching Hua Lee, Justin Jang Hann Chu

Immunology & Microbiology, MedicineNicholas LiaoMay 30, 20202019-10 (Oct)

Sodium Chloride Is an Ionic Checkpoint for Human TH2 Cells and Shapes the Atopic Skin Microenvironment

Sci Transl Med. 2019 Feb 20;11(480):eaau0683.

Julia Matthias, Julia Maul, Rebecca Noster … Tilo Biedermann, Dirk Baumjohann, Christina E Zielinski

Immunology & Microbiology, MedicineNicholas LiaoMay 29, 20202019-02 (Feb)

Comprehensive Analysis of a Mouse Model of Spontaneous Uveoretinitis Using Single-Cell RNA Sequencing

Proc Natl Acad Sci USA. 2019 Dec 16;116(52):26734-26744.

Jacob S Heng, Sean F Hackett, Genevieve L Stein-O'Brien, John Williams, Loyal A Goff, Jeremy Nathans

Immunology & MicrobiologyNicholas LiaoMay 28, 20202019-12 (Dec)

RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats.

Nat Neurosci. 2019 Sep;22(9):1383-1388.

Yamada SB, Gendron TF, Niccoli T, Isaacs AM, Petrucelli L, Gitler AD.

Neuroscience, Genetics & Genome BiologyNicholas LiaoMay 27, 20202019-09 (Sep)

Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery.

Nat Biotechnol. 2020 Jan;38(1):50-55.

Kyle V Butler, Anna M Chiarella, Berkley E Gryder ... Javed Khan, Jian Jin, Nathaniel A Hathaway

Genomics, Biochemistry, Genetics & Genome BiologyNicholas LiaoMay 25, 20202020-01 (Jan)

Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss.

Cell Metab. 2019 Aug 6;30(2):261-273.e6.

Lina Aguirre, Georgia Colleluori, Uma Phadnis ... Kevin Yarasheski, Clifford Qualls, Dennis T Villareal

MetabolismNicholas LiaoMay 24, 20202019-08 (Aug)

Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis.

Sci Transl Med. 2019 Nov 13;11(518).

Mishra R, Kohli S, Malhotra N, …, Rajmani RS, Seshasayee ASN, Singh A.

Medicine, Immunology & MicrobiologyNicholas LiaoMay 23, 20202019-11 (Nov)

A GBF1-Dependent Mechanism for Environmentally Responsive Regulation of ER-Golgi Transport.

Dev Cell. 2019 Jun 3;49(5):786-801.e6.

Mafalda Lopes-da-Silva, Jessica J McCormack, Jemima J Burden, Kimberly J Harrison-Lavoie, Francesco Ferraro, Daniel F Cutler

Cell & Developmental BioNicholas LiaoMay 21, 20202019-06 (Jun)

Localized Intercellular Transfer of Ephrin-As by Trans-endocytosis Enables Long-Term Signaling.

Dev Cell. 2020 Jan 6;52(1):104-117.e5.

José Ignacio Valenzuela, Franck Perez

Cell & Developmental BioNicholas LiaoMay 20, 20202020-01 (Jan)

Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut.

Dev Cell. 2019 Oct 7;51(1):7-20.e6.

Daniel S Levic, Jieun Park, Kaelyn D Sumigray ... Stephen A Watts, Terry Lechler, Michel Bagnat

Metabolism, Cell & Developmental BioNicholas LiaoMay 19, 20202019-10 (Oct)

Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas.

Dev Cell. 2019 Jan 7;48(1):115-125.e4.

Farack L, Golan M, Egozi A, …, Roitman L, Krizhanovsky V, Itzkovitz S.

Metabolism, Cell & Developmental BioNicholas LiaoMay 18, 20202019-01 (Jan)

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis.

Cell Metab. 2019 Oct 1;30(4):784-799.e5.

Chung KW, Dhillon P, Huang S, Baur J, Palmer M, Susztak K.

Metabolism, Cell & Developmental BioNicholas LiaoMay 17, 20202019-10 (Oct)

IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation.

Cell Host Microbe. 2019 Jun 12;25(6):858-872.e13.

Hotter D, Bosso M, Jønsson KL, …, Dittmer U, Sauter D, Kirchhoff F.

Immunology & MicrobiologyNicholas LiaoMay 16, 20202019-06 (Jun)