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Research Films RSS
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Adaptive immunity induces mutualism between commensal eukaryotes
Adaptive immunity induces mutualism between commensal eukaryotes

Nature. 2021 Aug;596(7870):114-118. doi: 10.1038/s41586-021-03722-w.

Kyla S Ost, Teresa R O'Meara, W Zac Stephens ... Noah W Palm, Suzanne M Noble, June L Round

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Immunology & MicrobiologyNicholas LiaoNovember 4, 20212021-08 (Aug)
Apc-mutant cells act as supercompetitors in intestinal tumour initiation
Apc-mutant cells act as supercompetitors in intestinal tumour initiation

Nature. 2021 Jun;594(7863):436-441. doi: 10.1038/s41586-021-03558-4.

Sanne van Neerven, Nina E de Groot, Lisanne E Nijman ... Edward Morrissey, Nicolas Léveillé, Louis Vermeulen

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Cancer BiologyNicholas LiaoNovember 2, 20212021-06 (Jun)
Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation
Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation

Cell. 2021 Sep 16;184(19):4886-4903.e21. doi: 10.1016/j.cell.2021.08.001.

Christopher D Reinkemeier, Edward A Lemke

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Biochemistry, BiotechnologyNicholas LiaoOctober 28, 20212021-08 (Aug)
Migration-induced cell shattering due to DOCK8 deficiency causes a type 2-biased helper T cell response
Migration-induced cell shattering due to DOCK8 deficiency causes a type 2-biased helper T cell response

Nat Immunol. 2020 Dec;21(12):1528-1539. doi: 10.1038/s41590-020-0795-1.

Caitlin Schneider, Connie Shen, Angelica A Gopal ... Paul W Wiseman, Helen C Su, Judith N Mandl

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Immunology & MicrobiologyNicholas LiaoOctober 26, 20212020-12 (Dec)
DNA-driven condensation assembles the meiotic DNA break machinery
DNA-driven condensation assembles the meiotic DNA break machinery

Nature. 2021 Apr;592(7852):144-149. doi: 10.1038/s41586-021-03374-w.

Corentin Claeys Bouuaert, Stephen Pu, Juncheng Wang ... Wei Xie, Dinshaw J Patel, Scott Keeney

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Genetics & Genome Biology, Cell & Developmental Bio, BiochemistryNicholas LiaoOctober 21, 20212021-04 (Apr)
HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults
HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults

Nat Med. 2021 Jun;27(6):1006-1011. doi: 10.1038/s41591-021-01357-y.

Nila J Dharan, Paul Yeh, Mark Bloch ... Mark N Polizzotto, Mark A Dawson, ARCHIVE Study Group

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Cancer Biology, MedicineNicholas LiaoOctober 19, 20212021-06 (Jun)
Creatine kinase B controls futile creatine cycling in thermogenic fat
Creatine kinase B controls futile creatine cycling in thermogenic fat

Nature. 2021 Feb;590(7846):480-485. doi: 10.1038/s41586-021-03221-y.

Janane F Rahbani, Anna Roesler, Mohammed F Hussain ... Karen Reue, Bruce M Spiegelman, Lawrence Kazak

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BiochemistryNicholas LiaoOctober 14, 20212021-02 (Feb)
Shared mechanisms underlie the control of working memory and attention
Shared mechanisms underlie the control of working memory and attention

Nature. 2021 Apr;592(7855):601-605. doi: 10.1038/s41586-021-03390-w.

Matthew F Panichello, Timothy J Buschman

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NeuroscienceNicholas LiaoOctober 12, 20212021-04 (Apr)
Cell-programmed nutrient partitioning in the tumour microenvironment
Cell-programmed nutrient partitioning in the tumour microenvironment

Nature. 2021 May;593(7858):282-288. doi: 10.1038/s41586-021-03442-1.

Bradley I Reinfeld, Matthew Z Madden, Melissa M Wolf ... H Charles Manning, Jeffrey C Rathmell, W Kimryn Rathmell

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Cancer Biology, MetabolismNicholas LiaoSeptember 23, 20212021-05 (May)
Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines
Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines

Cell Syst. 2021 Sep 10;S2405-4712(21)00329-X. doi: 10.1016/j.cels.2021.08.006.

Barbara De Kegel<sup>1</sup>, Niall Quinn<sup>1</sup>, Nicola A Thompson<sup>2</sup>, David J Adams<sup>2</sup>, Colm J Ryan<sup>3</sup>

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Cancer BiologyNicholas LiaoSeptember 21, 20212021-09
A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease
A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease

Nature. 2021 May;593(7858):275-281. doi: 10.1038/s41586-021-03484-5.

Shikha Nayar, Joshua K Morrison, Mamta Giri ... Miriam Merad, Jaime Chu, Judy H Cho

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Medicine, Immunology & MicrobiologyNicholas LiaoSeptember 16, 20212021-05 (May)
The distribution of cellular turnover in the human body
The distribution of cellular turnover in the human body

Nat Med. 2021 Jan;27(1):45-48. doi: 10.1038/s41591-020-01182-9.

Ron Sender, Ron Milo

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Medicine, Cell & Developmental BioNicholas LiaoSeptember 14, 20212021-01 (Jan)
Receptor-targeted engineered probiotics mitigate lethal Listeria infection
Receptor-targeted engineered probiotics mitigate lethal Listeria infection

Nat Commun. 2020 Dec 11;11(1):6344. doi: 10.1038/s41467-020-20200-5.

Rishi Drolia, Mary Anne Roshni Amalaradjou, Valerie Ryan ... Bruce M Applegate, Ramesh Vemulapalli, Arun K Bhunia

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MicrobiologyNicholas LiaoSeptember 2, 20212020-12 (Dec)
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child.
Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child.

Nat Med. 2021 Jun 28. doi: 10.1038/s41591-021-01388-5.

Masato Ogishi, Rui Yang, Caner Aytekin ... Philippe Gros, Stéphanie Boisson-Dupuis, Jean-Laurent Casanova

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Medicine, Immunology & MicrobiologyNicholas LiaoAugust 31, 20212021-06 (Jun)
AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion
AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

Nat Commun. 2020 Dec 11;11(1):6366. doi: 10.1038/s41467-020-20029-y.

Anne Schuster, Eliane Klein, Virginie Neirinckx ... Barbara Klink, Bjarne Winther Kristensen, Simone P Niclou

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Genomics, Medicine, NeuroscienceNicholas LiaoAugust 26, 20212020-12 (Dec)
Circulating transcripts in maternal blood reflect a molecular signature of early-onset preeclampsia
Circulating transcripts in maternal blood reflect a molecular signature of early-onset preeclampsia

Sci Transl Med. 2020 Jul 1;12(550):eaaz0131. doi: 10.1126/scitranslmed.aaz0131.

Sarah Munchel, Suzanne Rohrback, Carlo Randise-Hinchliff ... Ronald Wapner, George Saade, Fiona Kaper

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Medicine, GenomicsNicholas LiaoAugust 24, 20212020-07 (Jul)
Effective control of SARS-CoV-2 transmission in Wanzhou, China
Effective control of SARS-CoV-2 transmission in Wanzhou, China

Nat Med. 2021 Jan;27(1):86-93. doi: 10.1038/s41591-020-01178-5.

Qiuling Shi, Yaoyue Hu, Bin Peng ... Jing-Fu Qiu, Cheng Yong Yang, Ai-Long Huang

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COVID-19, MedicineNicholas LiaoAugust 19, 20212021-01 (Jan)
SPNS2 enables T cell egress from lymph nodes during an immune response
SPNS2 enables T cell egress from lymph nodes during an immune response

Cell Rep. 2021 Jul 13;36(2):109368. doi: 10.1016/j.celrep.2021.109368.

Martyna Okuniewska, Victoria Fang, Audrey Baeyens ... June-Yong Lee, Dan R Littman, Susan R Schwab

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Immunology & MicrobiologyNicholas LiaoAugust 17, 20212021-07 (Jul)
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