Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis

Immunity. 2021 Aug 10;54(8):1807-1824.e14. doi: 10.1016/j.immuni.2021.07.009.

Mark P Roberto, Gabriele Varano, Rosa Vinas-Castells ... Pedro Farinha, David W Scott, David Dominguez-Sola

Immunology & MicrobiologyNicholas LiaoJuly 21, 20222021-08 (Aug)

Antigen and checkpoint receptor engagement recalibrates T cell receptor signal strength

Immunity. 2021 Nov 9;54(11):2481-2496.e6. doi: 10.1016/j.immuni.2021.08.020.

Thomas A E Elliot, Emma K Jennings, David A J Lecky ... Kendle M Maslowski, David C Wraith, David Bending

Immunology & MicrobiologyNicholas LiaoJuly 19, 20222021-11 (Nov)

Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration

Cell Stem Cell. 2021 Nov 4;28(11):1982-1999.e8. doi: 10.1016/j.stem.2021.07.011.

Le Qi, Misty S Martin-Sandoval, Salma Merchant ... Zhiyu Zhao, Michalis Agathocleous, Sean J Morrison

Biochemistry, Cell & Developmental Bio, MetabolismNicholas LiaoJuly 14, 20222021-11 (Nov)

VTA dopamine neuron activity encodes social interaction and promotes reinforcement learning through social prediction error

Nat Neurosci. 2022 Jan;25(1):86-97. doi: 10.1038/s41593-021-00972-9.

Clément Solié, Benoit Girard, Beatrice Righetti, Malika Tapparel, Camilla Bellone

NeuroscienceNicholas LiaoJuly 12, 20222022-01 (Jan)

Massively parallel phenotyping of coding variants in cancer with Perturb-seq

Nat Biotechnol. 2022 Jun;40(6):896-905. doi: 10.1038/s41587-021-01160-7.

Oana Ursu, James T Neal, Emily Shea ... Alice H Berger, Aviv Regev, Jesse S Boehm

Cancer Biology, GenomicsNicholas LiaoJuly 7, 20222022-06 (Jun)

Continuous clonal labeling reveals uniform progenitor potential in the adult exocrine pancreas

Cell Stem Cell. 2021 Nov 4;28(11):2009-2019.e4. doi: 10.1016/j.stem.2021.07.004.

Sophie C Lodestijn, Tom van den Bosch, Lisanne E Nijman ... Douglas J Winton, Maarten F Bijlsma, Louis Vermeulen

Cell & Developmental BioNicholas LiaoJuly 5, 20222021-11 (Nov)

SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

Cell Stem Cell. 2022 Jan 6;29(1):101-115.e10. doi: 10.1016/j.stem.2021.09.004.

Wei Gu, Hua Wang, Xiaofeng Huang ... Kristian Helin, Ramesh A Shivdasani, Qiao Zhou

Cell & Developmental Bio, Genetics & Genome BiologyNicholas LiaoJune 30, 20222022-01 (Jan)

Targeted multicolor in vivo imaging over 1,000 nm enabled by nonamethine cyanines

Nat Methods. 2022 Mar;19(3):353-358. doi: 10.1038/s41592-022-01394-6.

Venu G Bandi, Michael P Luciano, Mara Saccomano ... Joseph Ivanic, Oliver T Bruns, Martin J Schnermann

BiotechnologyNicholas LiaoJune 28, 20222022-03 (Mar)

Robust single-cell discovery of RNA targets of RNA-binding proteins and ribosomes

Nat Methods. 2021 May;18(5):507-519. doi: 10.1038/s41592-021-01128-0.

Kristopher W Brannan, Isaac A Chaim, Ryan J Marina ... Assael A Madrigal, Jason G Underwood, Gene W Yeo

Biochemistry, Biotechnology, Genetics & Genome Biology, GenomicsNicholas LiaoJune 23, 20222021-05 (May)

Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity

Nat Immunol. 2021 Sep;22(9):1140-1151. doi: 10.1038/s41590-021-01004-1.

Susan N Christo, Maximilien Evrard, Simone L Park ... Francis R Carbone, Axel Kallies, Laura K Mackay

Immunology & MicrobiologyNicholas LiaoJune 21, 20222021-09 (Sep)

Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension

Cell Metab. 2021 Jun 1;33(6):1155-1170.e10. doi: 10.1016/j.cmet.2021.04.007.

Tim Gruber, Chenchen Pan, Raian E Contreras ... Tamas L Horvath, Matthias H Tschöp, Cristina García-Cáceres

Metabolism, NeuroscienceNicholas LiaoJune 16, 20222021-07 (Jul)

Morphine acts on spinal dynorphin neurons to cause itch through disinhibition

Sci Transl Med. 2021 Feb 3;13(579):eabc3774. doi: 10.1126/scitranslmed.abc3774.

Eileen Nguyen, Grace Lim, Huiping Ding, Junichi Hachisuka, Mei-Chuan Ko, Sarah E Ross

Medicine, NeuroscienceNicholas LiaoJune 14, 20222021-02 (Feb)

Single-cell landscapes of primary glioblastomas and matched explants and cell lines show variable retention of inter- and intratumor heterogeneity

Cancer Cell. 2022 Apr 11;40(4):379-392.e9. doi: 10.1016/j.ccell.2022.02.016.

Véronique G LeBlanc, Diane L Trinh, Shaghayegh Aslanpour ... Jennifer A Chan, John J P Kelly, Marco A Marra

Cancer BiologyNicholas LiaoJune 9, 20222022-04 (Apr)

A PARTHENOGENESIS allele from apomictic dandelion can induce egg cell division without fertilization in lettuce

Nat Genet. 2022 Jan;54(1):84-93. doi: 10.1038/s41588-021-00984-y.

Charles J Underwood, Kitty Vijverberg, Diana Rigola ... Marcel Prins, M Eric Schranz, Peter J van Dijk

Cell & Developmental Bio, Genetics & Genome BiologyNicholas LiaoJune 7, 20222022-01 (Jan)

A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging

Nat Neurosci. 2021 Sep;24(9):1324-1337. doi: 10.1038/s41593-021-00895-5.

Peter Rupprecht, Stefano Carta, Adrian Hoffmann ... Kazuo Kitamura, Fritjof Helmchen, Rainer W Friedrich

NeuroscienceNicholas LiaoJune 2, 20222021-09 (Sep)

Compartmentalized dynamics within a common multi-area mesoscale manifold represent a repertoire of human hand movements

Neuron. 2022 Jan 5;110(1):154-174.e12. doi: 10.1016/j.neuron.2021.10.002.

Nikhilesh Natraj, Daniel B Silversmith, Edward F Chang, Karunesh Ganguly

NeuroscienceNicholas LiaoMay 31, 20222022-01 (Jan)

An intracortical neuroprosthesis immediately alleviates walking deficits and improves recovery of leg control after spinal cord injury

Sci Transl Med. 2021 Mar 24;13(586):eabb4422. doi: 10.1126/scitranslmed.abb4422.

Marco Bonizzato, Marina Martinez

NeuroscienceNicholas LiaoMay 26, 20222021-03 (Mar)

Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

Cancer Cell. 2022 Mar 14;40(3):318-334.e9. doi: 10.1016/j.ccell.2022.01.002.

Assia Asrir, Claire Tardiveau, Juliette Coudert ... Nathalie Ortega, Caroline Robert, Jean-Philippe Girard

Cancer Biology, Immunology & MicrobiologyNicholas LiaoMay 24, 20222022-03 (Mar)