Posts in Medicine

Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes.

Cell Metab. 2019 Sep 3;30(3):447-461.e5.

Nicholas DA, Proctor EA, Agrawal M…Kern PA, Lauffenburger DA, Nikolajczyk BS.

Metabolism, Medicine, Immunology & MicrobiologyNicholas LiaoMay 15, 20202019-09 (Sep)

Protein Kinase C Quality Control by Phosphatase PHLPP1 Unveils Loss-of-Function Mechanism in Cancer.

Mol Cell. 2019 Apr 18;74(2):378-392.e5.

Baffi TR, Van AN, Zhao W, Mills GB, Newton AC.

Biochemistry, Cancer Biology, MedicineDavid CantorMarch 25, 20202019-04 (Apr)

Adaptive mutability of colorectal cancers in response to targeted therapies.

Science. 2019 Dec 20;366(6472):1473-1480

Russo M, Crisafulli G, Sogari A, Reilly NM, Arena S…Lagomarsino MC, Di Nicolantonio F, Bardelli A.

Cancer Biology, MedicineVictoria FangMarch 3, 2020

Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women

Cell. 2019 Jun 27;178(1):190-201.e11.

Martinez DR, Fong Y, Li SH, Yang F, Jennewein MF, Weiner JA, Harrell EA, Mangold JF, Goswami R, Seage GR 3rd, Alter G, Ackerman ME, Peng X, Fouda GG, Permar SR.

Biochemistry, Immunology & Microbiology, MedicineVictoria FangJanuary 30, 20202019-06 (Jun)

Multispecific anti-HIV duoCAR-T cells display broad in vitro antiviral activity and potent in vivo elimination of HIV-infected cells in a humanized mouse model.

Sci Transl Med. 2019 Aug 7;11(504).

Anthony-Gonda K#, Bardhi A#, Ray A, Flerin N, Li M… Dimitrov DS, Goldstein H, Dropulić B.

Immunology & Microbiology, Medicine, BiochemistryVictoria FangJanuary 29, 20202019-08 (Aug)

A Reverse Ecology Approach Based on a Biological Definition of Microbial Populations

Cell. 2019 Aug 8;178(4):820-834.e14

Arevalo P, VanInsberghe D, Elsherbini J, Gore J, Polz MF.

Genomics, Medicine, Immunology & Microbiology, Genetics & Genome BiologyVictoria FangJanuary 16, 20202019-08 (Aug)

A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling

Zhao Y, Rafatian N, Feric NT, Cox BJ, Aschar-Sobbi R, Wang EY, Aggarwal P, Zhang B, Conant G, Ronaldson-Bouchard K, Pahnke A, Protze S, Lee JH, Davenport Huyer L, Jekic D, Wickeler A, Naguib HE, Keller GM, Vunjak-Novakovic G, Broeckel U, Backx PH, Radisic M.

Cell. 2019 Feb 7;176(4):913-927.e18

Cell & Developmental Bio, MedicineVictoria FangDecember 9, 20192019-02 (Feb)

Identifying Epistasis in Cancer Genomes: A Delicate Affair

van de Haar J, Canisius S, Yu MK, Voest EE, Wessels LFA, Ideker T.

Cell. 2019 May 30;177(6):1375-1383.

Cancer Biology, Medicine, Genetics & Genome BiologyVictoria FangNovember 18, 20192019-05 (May)

A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation.

Fernandez IZ#, Baxter RM#, Garcia-Perez JE, Vendrame E, Ranganath T, Kong DS, Lundquist K, Nguyen T, Ogolla S, Black J, Galambos C, Gumbart JC, Dawany N, Kelsen JR, de Zoeten EF, Quinones R, Eissa H, Verneris MR, Sullivan KE, Rochford R, Blish CA, Kedl RM*, Dutmer CM*, Hsieh EWY*.

# Contributed equally, * Contributed equally

J Exp Med. 2019 Jun 3;216(6):1255-1267.

Immunology & Microbiology, Medicine, Genetics & Genome BiologyVictoria FangOctober 18, 20192019-06 (Jun)

A multimodality test to guide the management of patients with a pancreatic cyst.

Springer S, Masica DL, Dal Molin M, Douville C, Thoburn CJ…Klein AP, Tomasetti C, Karchin R, Papadopoulos N, Kinzler KW, Vogelstein B, Wolfgang CL, Hruban RH, Lennon AM.

Sci Transl Med. 2019 Jul 17;11(501).

Medicine, Cancer BiologyVictoria FangOctober 8, 20192019-07 (Jul)