Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4 + T Cell Pathogenicity and Suppresses Autoimmunity

Cell Metab. 2020 Feb 4;31(2):391-405.e8.

Stefano Angiari, Marah C Runtsch, Caroline E Sutton ... Erika L Pearce, Kingston H G Mills, Luke A J O'Neill

Immunology & Microbiology, MetabolismNicholas LiaoJune 15, 20202020-02 (Feb)

HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding

Mol Cell. 2019 Aug 22;75(4):711-724.e5. doi: 10.1016/j.molcel.2019.05.034.

Joshua J Gruber, Benjamin Geller, Andrew M Lipchik ... James M Ford, Calvin J Kuo, Michael P Snyder

Biochemistry, Metabolism, Genetics & Genome BiologyNicholas LiaoJune 13, 20202019-08 (Aug)

FBP1 Loss Disrupts Liver Metabolism and Promotes Tumorigenesis Through a Hepatic Stellate Cell Senescence Secretome

Nat Cell Biol. 2020 May 4.

Fuming Li, Peiwei Huangyang, Michelle Burrows … Brian Keith, Bo Li, M Celeste Simon

Cancer Biology, MetabolismNicholas LiaoJune 1, 20202020-05 (May)

Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss.

Cell Metab. 2019 Aug 6;30(2):261-273.e6.

Lina Aguirre, Georgia Colleluori, Uma Phadnis ... Kevin Yarasheski, Clifford Qualls, Dennis T Villareal

MetabolismNicholas LiaoMay 24, 20202019-08 (Aug)

Lysosome-Rich Enterocytes Mediate Protein Absorption in the Vertebrate Gut.

Dev Cell. 2019 Oct 7;51(1):7-20.e6.

Daniel S Levic, Jieun Park, Kaelyn D Sumigray ... Stephen A Watts, Terry Lechler, Michel Bagnat

Metabolism, Cell & Developmental BioNicholas LiaoMay 19, 20202019-10 (Oct)

Transcriptional Heterogeneity of Beta Cells in the Intact Pancreas.

Dev Cell. 2019 Jan 7;48(1):115-125.e4.

Farack L, Golan M, Egozi A, …, Roitman L, Krizhanovsky V, Itzkovitz S.

Metabolism, Cell & Developmental BioNicholas LiaoMay 18, 20202019-01 (Jan)

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis.

Cell Metab. 2019 Oct 1;30(4):784-799.e5.

Chung KW, Dhillon P, Huang S, Baur J, Palmer M, Susztak K.

Metabolism, Cell & Developmental BioNicholas LiaoMay 17, 20202019-10 (Oct)

Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes.

Cell Metab. 2019 Sep 3;30(3):447-461.e5.

Nicholas DA, Proctor EA, Agrawal M…Kern PA, Lauffenburger DA, Nikolajczyk BS.

Metabolism, Medicine, Immunology & MicrobiologyNicholas LiaoMay 15, 20202019-09 (Sep)

Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis.

Cell Metab. 2020 Jan 7;31(1):174-188.e7.

Huangyang P, Li F, Lee P, Keith B, Yoon SS, Simon MC.

Cancer Biology, MetabolismNicholas LiaoMay 4, 20202020-01 (Jan)

Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring.

Cell Metab. 2019 Dec 3;30(6):1055-1074.e8.

Pucino V, Certo M, Bulusu V, Bombardieri M, Pitzalis C, Mauro C.

Immunology & Microbiology, MetabolismNicholas LiaoApril 24, 20202019-12 (Dec)

An elusive electron shuttle from a facultative anaerobe

Elife. 2019 Jun 24;8. pii: e48054

Mevers E#, Su L#, Pishchany G, Baruch M, Cornejo J, Hobert E, Dimise E, Ajo-Franklin CM, Clardy J.

#Contributed equally

Biochemistry, Immunology & Microbiology, MetabolismVictoria FangJanuary 24, 20202019-06 (Jun)

High Dietary Sugar Reshapes Sweet Taste to Promote Feeding Behavior in Drosophila melanogaster

Cell Rep. 2019 May 7;27(6):1675-1685.e7

May CE, Vaziri A, Lin YQ, Grushko O, Khabiri M, Wang QP, Holme KJ, Pletcher SD, Freddolino PL, Neely GG, Dus M.

Neuroscience, MetabolismVictoria FangJanuary 21, 20202019-05 (May)

Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet

Cell. 2019 Aug 22;178(5):1115-1131.e15.

Cheng CW, Biton M, Haber AL, Gunduz N, Eng G, Gaynor LT, Tripathi S, Calibasi-Kocal G, Rickelt S, Butty VL, Moreno-Serrano M…Regev A, Yilmaz ÖH.

Metabolism, Cell & Developmental BioVictoria FangJanuary 10, 20202019-08 (Aug)

Time of Exercise Specifies the Impact on Muscle Metabolic Pathways and Systemic Energy Homeostasis

Cell Metab. 2019 Jul 2;30(1):92-110.e4

Sato S, Basse AL, Schönke M, Chen S, Samad M, Altıntaş A, Laker RC, Dalbram E, Barrès R, Baldi P, Treebak JT, Zierath JR, Sassone-Corsi P.

MetabolismVictoria FangJanuary 7, 20202019-07 (Jul)

Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47-mediated 'don't-eat-me' signal

Liu M, O'Connor RS, Trefely S, Graham K, Snyder NW, Beatty GL.

Nat Immunol. 2019 Jan 21;20(3):265-275.

Cancer Biology, Immunology & Microbiology, MetabolismVictoria FangDecember 2, 20192019-01 (Jan)

Defining the Independence of the Liver Circadian Clock

Koronowski KB, Kinouchi K, Welz PS, Smith JG, Zinna VM, Shi J, Samad M, Chen S, Magnan CN, Kinchen JM, Li W, Baldi P, Benitah SA, Sassone-Corsi P.

Cell. 2019 May 30;177(6):1448-1462.e14.

MetabolismVictoria FangNovember 13, 20192019-05 (May)