AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment

Nature. 2020 Apr;580(7805):647-652. doi: 10.1038/s41586-020-2174-3.

Catherine R Lammert, Elizabeth L Frost, Calli E Bellinger ... Matt J Paysour, Hannah E Ennerfelt, John R Lukens

Neuroscience, Cell & Developmental BioNicholas LiaoJuly 22, 20202020-04 (Apr)

NAD+ Regeneration Rescues Lifespan, but Not Ataxia, in a Mouse Model of Brain Mitochondrial Complex I Dysfunction

Cell Metab. 2020 Jun 16;S1550-4131(20)30304-1. doi: 10.1016/j.cmet.2020.06.003.

Gregory S McElroy, Colleen R Reczek, Paul A Reyfman, Divakar S Mithal, Craig M Horbinski, Navdeep S Chandel

Metabolism, NeuroscienceNicholas LiaoJuly 16, 20202020-06 (Jun)

Integrative Transcriptomics Reveals Sexually Dimorphic Control of the Cholinergic/Neurokine Interface in Schizophrenia and Bipolar Disorder

Cell Rep. 2019 Oct 15;29(3):764-777.e5. doi: 10.1016/j.celrep.2019.09.017.

Sebastian Lobentanzer, Geula Hanin, Jochen Klein, Hermona Soreq

Neuroscience, GenomicsNicholas LiaoJuly 10, 20202019-10 (Oct)

A Farnesyltransferase Inhibitor Activates Lysosomes and Reduces Tau Pathology in Mice With Tauopathy

Sci Transl Med. 2019 Mar 27;11(485):eaat3005.

Israel Hernandez, Gabriel Luna, Jennifer N Rauch ... Steven K Fisher, Ana M Cuervo, Kenneth S Kosik

NeuroscienceNicholas LiaoJune 11, 20202019-03 (Mar)

The Long Noncoding RNA Pnky Is a Trans-acting Regulator of Cortical Development In Vivo

Dev Cell. 2019 May 20;49(4):632-642.e7.

Rebecca E Andersen, Sung Jun Hong, Justin J Lim … Siyuan John Liu, Benjamin J Blencowe, Daniel A Lim

Cell & Developmental Bio, NeuroscienceNicholas LiaoJune 6, 20202019-05 (May)

RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats.

Nat Neurosci. 2019 Sep;22(9):1383-1388.

Yamada SB, Gendron TF, Niccoli T, Isaacs AM, Petrucelli L, Gitler AD.

Neuroscience, Genetics & Genome BiologyNicholas LiaoMay 27, 20202019-09 (Sep)

NLRP3 inflammasome activation drives tau pathology.

Nature. 2019 Nov;575(7784):669-673.

Ising C, Venegas C, Zhang S, Latz E, Buée L, Heneka MT.

Neuroscience, BiochemistryNicholas LiaoApril 28, 20202019-11 (Nov)

A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.

Nat Neurosci. 2019 Jun;22(6):1021-1035.

Van Hove H, Martens L, Scheyltjens I, Van Ginderachter JA, Saeys Y, Movahedi K.

NeuroscienceNicholas LiaoApril 17, 20202019-06 (Jun)

TREM2 function impedes tau seeding in neuritic plaques.

Nat Neurosci. 2019 Aug;22(8):1217-1222.

Leyns CEG, Gratuze M, Narasimhan S, Jain N, Koscal LJ, Jiang H, Manis M, Colonna M, Lee VMY, Ulrich JD, Holtzman DM.

NeuroscienceVictoria FangMarch 20, 20202019-08 (Aug)

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models.

Nat Neurosci. 2019 Mar;22(3):413-420

Cruz Hernández JC#, Bracko O#, Kersbergen CJ, Muse V, Haft-Javaherian M…Nishimura N, Schaffer CB.

#Contributed equally

NeuroscienceVictoria FangMarch 5, 20202019-03 (Mar)

Microglia monitor and protect neuronal function through specialized somatic purinergic junctions.

Science. 2020 Jan 31;367(6477):528-537

Cserép C#, Pósfai B#, Lénárt N, Fekete R, László ZI… Katona I, Liesz A, Tamás G, Dénes Á.

#Contributed equally

Neuroscience, Cell & Developmental BioVictoria FangMarch 2, 20202020-01 (Jan)

Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit

Cell Stem Cell. 2020 Apr 2;26(4):558-568.e9. doi: 10.1016/j.stem.2020.01.018.

Christopher S Morrow, Tiaira J Porter, Nan Xu ... Helen J Heo, Elizabeth A N Thompson, Darcie L Moore

Cell & Developmental Bio, NeuroscienceVictoria FangFebruary 27, 20202020-02 (Feb)

High Dietary Sugar Reshapes Sweet Taste to Promote Feeding Behavior in Drosophila melanogaster

Cell Rep. 2019 May 7;27(6):1675-1685.e7

May CE, Vaziri A, Lin YQ, Grushko O, Khabiri M, Wang QP, Holme KJ, Pletcher SD, Freddolino PL, Neely GG, Dus M.

Neuroscience, MetabolismVictoria FangJanuary 21, 20202019-05 (May)

Sour Sensing from the Tongue to the Brain

Zhang J, Jin H, Zhang W, Ding C, O'Keeffe S, Ye M, Zuker CS.

Cell. 2019 Oct 3;179(2):392-402.e15.

NeuroscienceVictoria FangDecember 17, 20192019-10 (Oct)

Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation

Wheeler MA, Jaronen M, Covacu R, Zandee SEJ, Scalisi G, Rothhammer V, Tjon EC, Chao CC, Kenison JE, Blain M, Rao VTS, Hewson P, Barroso A, Gutiérrez-Vázquez C, Prat A, Antel JP, Hauser R, Quintana FJ.

Cell. 2019 Jan 24;176(3):581-596.e18.

Immunology & Microbiology, NeuroscienceVictoria FangNovember 20, 20192019-01 (Jan)

Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis.

Henderson MX, Cornblath EJ, Darwich A, Zhang B, Brown H, Gathagan RJ, Sandler RM, Bassett DS, Trojanowski JQ, Lee VMY.

Nat Neurosci. 2019 Aug;22(8):1248-1257.

NeuroscienceVictoria FangNovember 5, 20192019-08 (Aug)

Transient, Consequential Increases in Extracellular Potassium Ions Accompany Channelrhodopsin2 Excitation

Octeau JC, Gangwani MR, Allam SL, Tran D, Huang S, Hoang-Trong TM, Golshani P, Rumbell TH, Kozloski JR, Khakh BS.

Cell Rep. 2019 May 21;27(8):2249-2261.e7

NeuroscienceVictoria FangNovember 2, 20192019-05 (May)

Sub-second dynamics of theta-gamma coupling in hippocampal CA1

Elife. 2019 Jul 29;8:e44320. doi: 10.7554/eLife.44320.

Lu Zhang, John Lee, Christopher Rozell, Annabelle C Singer

NeuroscienceVictoria FangOctober 1, 20192019-07 (Jul)